モエキシプリル塩酸塩
モエキシプリル塩酸塩 物理性質
- 融点 :
- 141-1610C
- 比旋光度 :
- D23 +34.2° (c = 1.1 in ethanol)
- 貯蔵温度 :
- 2-8°C
- 溶解性:
- H2O: 可溶32mg/mL
- 外見 :
- 粉
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 主な危険性 |
N |
|
|
| Rフレーズ |
50 |
|
|
| Sフレーズ |
60 |
|
|
| RIDADR |
UN 3077 9/PG 3 |
|
|
| WGK Germany |
3 |
|
|
| RTECS 番号 |
NW7174500 |
|
|
| HSコード |
2933492250 |
|
|
| 絵表示（GHS） |
|
| 注意喚起語 |
警告 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H400 |
水生生物に強い毒性 |
水生環境有害性、急性毒性 |
1 |
警告 |
|
P273, P391, P501 |
|
| 注意書き |
| P273 |
環境への放出を避けること。 |
| P391 |
漏出物を回収すること。 |
| P501 |
内容物/容器を．．．に廃棄すること。 |
|
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCM485350 |
モエキシプリル塩酸塩
Moexipril Hydrochloride |
82586-52-5 |
25mg |
￥29700 |
2023-06-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCM485350 |
モエキシプリル塩酸塩
Moexipril Hydrochloride |
82586-52-5 |
50mg |
￥45100 |
2023-06-01 |
購入 |
|
Sigma-Aldrich Japan
|
M0821 |
モエキシプリル 塩酸塩 powder, ≥98% (HPLC)
Moexipril hydrochloride powder, ≥98% (HPLC) |
82586-52-5 |
50mg |
￥22400 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
1445426 |
モエキシプリル 塩酸塩 United States Pharmacopeia (USP) Reference Standard
Moexipril hydrochloride United States Pharmacopeia (USP) Reference Standard |
82586-52-5 |
100mg |
￥55400 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCM485350 |
モエキシプリル塩酸塩
Moexipril Hydrochloride |
82586-52-5 |
5mg |
￥18300 |
2024-03-01 |
購入 |
モエキシプリル塩酸塩 化学特性,用途語,生産方法
効能
血圧降下薬, アンジオテンシン変換酵素(ACE)阻害薬
説明
Moexipril hydrochloride is a novel ACE inhibitor first marketed in the U.S.A. for
the treatment of hypertension as a monotherapy and as a second-line therapy in
combination with diuretics or calcium antagonists. Like other ACE inhibitors, moexipril
is a prodrug that is converted in the liver to its diacid moexiprilat which is the active
agent. Moexipril displays a higher in vitro inhibitory potency to ACE than enalapril
although its effectiveness in reduction of blood pressure in hypertensive patients is
similar to that seen with enalapril. It is orally active with a rapid onset and prolonged
duration of action. Excellent tolerability has been reported. Moexipril is distinguished
by its lower cost than other marketed ACE inhibitors.
化学的特性
Crystalline Solid
使用
Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril
危険性
Moderately toxic by ingestion.
生物活性
Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC 50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.
モエキシプリル塩酸塩 上流と下流の製品情報
原材料
準備製品
モエキシプリル塩酸塩 生産企業
Global( 146)Suppliers
モエキシプリル塩酸塩 スペクトルデータ(1HNMR)
82586-52-5(モエキシプリル塩酸塩)キーワード:
- 82586-52-5
- (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
- 2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylicacidhydrochloride
- 3-Isoquinolinecarboxylicacid,2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]aMino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-,hydrochloride (1:1), (3S)-
- (3S)- 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid,hydrochloride (1:1)
- RS-10085
- Moexipril Hydrochloride (100 mg)
- Moexipril hydrochloride, >=99%
- (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenyl-d5-propyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic Acid Hydrochloride
- CI-925
- Fempress
- Perdix
- RS-10085-197
- SPM-925
- Univasc
- (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic Acid Hydrochloride
- (3S)-2-[(2S)-2-[[(1S)-1-carbethoxy-3-phenyl-propyl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
- (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenyl-butan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
- MOEXIPRIL HYDROCHLORIDE
- UNIVASC;RS10085;RS 10085;RS-10085
- (3S)-2-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-Phenyl-Propyl]Amino]Propanoyl]-6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinoline-3-Carboxylic Acid Hydrochloride
- 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid, hydrochloride
- MOEXIPRIL HYDROCHLORIDE USP/EP/BP
- (S)-2-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
- Moexipril HCl (RS-10085)
- (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan
-2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetr
ahydroisoquinoline-3-carboxylic acid
hydrochloride
- Moexipril HydrochlorideQ: What is
Moexipril Hydrochloride Q: What is the CAS Number of
Moexipril Hydrochloride Q: What is the storage condition of
Moexipril Hydrochloride Q: What are the applications of
Moexipril Hydrochloride
- Moexipril Hydrochloride (1445426)
- orally active,Apoptosis,Ischemic brain injury,inhibit,hepatic disease,RS10085,Angiotensin-converting Enzyme (ACE),hydrochlorothiazide,essential hypertension,Moexipril hydrochloride,antihypertensive,moexiprilat,angiotensin II,cardiovascular disease,RS 10085,Inhibitor,hypertension,Moexipril
- モエキシプリル塩酸塩
- モエキシプリル 塩酸塩
- 塩酸モエキシプリル
- (3S)-2-[(S)-2-[[(S)-1-(エトキシカルボニル)-3-フェニルプロピル]アミノ]-1-オキソプロピル]-1,2,3,4-テトラヒドロ-6,7-ジメトキシ-3-イソキノリンカルボン酸・塩酸塩
- ウニバスク