APOLIPOPROTEIN A-I, HUMAN
APOLIPOPROTEIN A-I, HUMAN 物理性質
- 貯蔵温度 :
- −20°C
- 溶解性:
- H2O: 1 mg/mL 無色透明
- 外見 :
- ソリューション (クリア)
- 色:
- 無色
安全性情報
APOLIPOPROTEIN A-I, HUMAN 価格
メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
Sigma-Aldrich Japan
|
SAB2502171 |
affinity isolated antibody, buffered aqueous solution
Anti-APOA1 antibody produced in goat affinity isolated antibody, buffered aqueous solution |
|
100μG |
¥95300 |
2023-06-01 |
購入 |
APOLIPOPROTEIN A-I, HUMAN 化学特性,用途語,生産方法
使用
Apolipoprotein A-I human has been used in the cholesterol efflux assay.
一般的な説明
ApoA-I, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis. For this reason HDL is also known as the "good cholesterol." The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.
Biochem/physiol Actions
ApoA-I (apolipoprotein A-I), which is found exclusively in HDL (high-density lipoprotein), has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is thought to inhibit atherogenesis. For this reason HDL is also known as the "good cholesterol." The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases. Changes in the level of serum apoA-I may serve as a prognostic marker for non-metastatic nasopharyngeal carcinoma. Low levels of apoA-I in the plasma is linked to hyperhomocysteinemia.
APOLIPOPROTEIN A-I, HUMAN 上流と下流の製品情報
原材料
準備製品
APOLIPOPROTEIN A-I, HUMAN 生産企業
Global( 45)Suppliers
- C117399
- MGC117399
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- HUMAN APOLIPOPROTEIN A I (MASS CONCENTRATION)
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- APO-A1, HUMAN PLASMA
- APO A-I
- APO A-I, HUMAN
- APO A-I HUMAN PLASMA
- APOLIPOPROTEIN A-1
- APOLIPOPROTEIN AI
- APOLIPOPROTEIN A-I, HUMAN
- APOLIPOPROTEIN A-I, HUMAN (66-86)
- APOLIPOPROTEIN A-I HUMAN PLASMA
- APOLIPOPROTEIN A-I, HUMAN PLASMA, HIGH-DENSITY LIPOPROTEIN
- APOLIPROTEIN A-I
- Anti-APOA1 antibody produced in goat
- ApoA-1 from rat
- Apolipoprotein A-I histidine-tagged
- Recombinant Human ApolipoProtein A-I/ApoA1 Protein, His Tag
- Human Apoa1 Protein, His Tag
- Human Apoa1 Protein, Fc Tag