Triamcinolone 21-acetate

 化学構造式
3859-65-2
CAS番号.
3859-65-2
化学名:
别名:
英語名:
Triamcinolone 21-acetate
英語别名:
BNKY017-TA02;Triamcinolone 21-Acetate;Triamcinolone EP Impurity B;Triamcinolone Impurity 2 (Triamcinolone EP Impurity B);9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate;(11β,16α)-21-acetyloxy-9-fluoro-11,16,17-trihydroxypegna-1,4-diene-3,20-dione;(11β,16α)-21-acetyloxy-9-fluoro-11,16,17-trihydroxypegna-1,4-diene-3,20-dione;Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,16,17-trihydroxy-, (11β,16α)-;9-fluoro-11β,16α,17-trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate (triamcinolone 21-acetate);2-((8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
CBNumber:
CB91452896
化学式:
C23H29FO7
分子量:
436.47
MOL File:
3859-65-2.mol

Triamcinolone 21-acetate 物理性質

融点 :
212-215 °C(Solv: acetone (67-64-1); ethyl ether (60-29-7))
沸点 :
596.0±50.0 °C(Predicted)
比重(密度) :
1.38±0.1 g/cm3(Predicted)
溶解性:
DMSO (Slightly), Methanol (Slightly, Sonicated, Heated)
外見 :
Solid
酸解離定数(Pka):
11.52±0.70(Predicted)
色:
White to Off-White

安全性情報

Triamcinolone 21-acetate 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

Triamcinolone 21-acetate 化学特性,用途語,生産方法

説明

Triamcinolone 21-acetate is a synthetic anti-inflammatory drug with a triamcinolone core. It has been used for the treatment of inflammatory conditions such as arthritis and allergic disorders. The mechanism of action is unknown, but it is thought to involve the inhibition of prostaglandin synthesis by inhibiting enzymes that are involved in prostaglandin biosynthesis. Triamcinolone 21-acetate is effective against rheumatoid arthritis and other inflammatory disorders. This drug also has anti-bacterial activity, which may be due to its ability to inhibit cell membrane function or interfere with protein synthesis.

使用

Triamcinolone 21-Acetate is an impurity of Triamcinolone (T767160), a glucocorticoid used as an antiasthmatic.

Triamcinolone 21-acetate 上流と下流の製品情報

原材料

準備製品


Triamcinolone 21-acetate 生産企業

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  • 3859-65-2
  • 9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate
  • Triamcinolone EP Impurity B
  • (11β,16α)-21-acetyloxy-9-fluoro-11,16,17-trihydroxypegna-1,4-diene-3,20-dione
  • BNKY017-TA02
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,16,17-trihydroxy-, (11β,16α)-
  • 2-((8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
  • Triamcinolone 21-Acetate
  • (11β,16α)-21-acetyloxy-9-fluoro-11,16,17-trihydroxypegna-1,4-diene-3,20-dione
  • 9-fluoro-11β,16α,17-trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate (triamcinolone 21-acetate)
  • 2-((8S,9R,10S,11S,13S,14S,16R,17S)-9-Fluoro-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate (Triamcinolone Impurity)
  • Triamcinolone Impurity 2 (Triamcinolone EP Impurity B)
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