Tie-2 Inhibitor 7

 化学構造式
1020412-97-8
CAS番号.
1020412-97-8
化学名:
别名:
英語名:
Tie-2 Inhibitor 7
英語别名:
Tie2 inhibitor;Tie inhibitor 7;Tie-2 Inhibitor 7;TIE2 INHIBITOR;TIE INHIBITOR 7;Tie2 Inhibitor 7,Tie-2 Inhibitor 7;(S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinic acid;3-Pyridinecarboxylic acid, 5-[4-[[[2-[[(1S)-1-cyclohexylethyl]amino]-2-oxoethyl][(4-methylphenoxy)carbonyl]amino]methyl]phenyl]-
CBNumber:
CB92684135
化学式:
C31H35N3O5
分子量:
529.63
MOL File:
1020412-97-8.mol

Tie-2 Inhibitor 7 物理性質

貯蔵温度 :
Store at -20°C
溶解性:
DMF: 14 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:9): 0.1 mg/ml; Ethanol: 1 mg/ml
外見 :
A crystalline solid

安全性情報

Tie-2 Inhibitor 7 価格

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Tie-2 Inhibitor 7 化学特性,用途語,生産方法

説明

Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.

Tie-2 Inhibitor 7 上流と下流の製品情報

原材料

準備製品


Tie-2 Inhibitor 7 生産企業

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  • 1020412-97-8
  • Tie-2 Inhibitor 7
  • Tie inhibitor 7
  • Tie2 inhibitor
  • TIE2 INHIBITOR;TIE INHIBITOR 7
  • (S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinic acid
  • 3-Pyridinecarboxylic acid, 5-[4-[[[2-[[(1S)-1-cyclohexylethyl]amino]-2-oxoethyl][(4-methylphenoxy)carbonyl]amino]methyl]phenyl]-
  • Tie2 Inhibitor 7,Tie-2 Inhibitor 7
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