Tie-2 Inhibitor 7 化学特性,用途語,生産方法
説明
Tie2 Inhibitor 7 blocks Tie2 kinase activity with a K
i value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC
50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.
Tie-2 Inhibitor 7 上流と下流の製品情報
原材料
準備製品