エルロチニブ

エルロチニブ 価格 もっと(2)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	SML3621	≥98% (HPLC) Erlotinib ≥98% (HPLC)	183321-74-6	50MG	￥11300	2023-06-01	購入
Sigma-Aldrich Japan	SML3621	≥98% (HPLC) Erlotinib ≥98% (HPLC)	183321-74-6	250MG	￥42600	2023-06-01	購入

エルロチニブ 化学特性,用途語,生産方法

効能

抗悪性腫瘍薬, 受容体チロシンキナーゼ阻害薬

説明

Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC₅₀ = 2.5 μM). This inhibits tumor growth in human head and neck carcinoma HN5 tumor xenografts in mice with an ED₅₀ value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC₅₀ = 4.6 μM) and JAK2 mutant JAK2^V617F positive hematopoietic progenitor cells (IC₅₀ = 5 μM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. Formulations containing erlotinib have been used to treat certain forms of cancer, including non-small cell lung cancer.

使用

Erlotinib HCl is an HER1/EGFR inhibitor with IC50 of 2 nM.

定義

ChEBI: A quinazoline compound having a (3-ethynylphenyl)amino group at the 4-position and two 2-methoxyethoxy groups at the 6- and 7-positions.

一般的な説明

Class: receptor tyrosine kinase
Treatment: NSCLC
Oral bioavailability = 60%
Elimination half-life = 36 h
Protein binding = 93%

副作用

• Burning, tingling, numbness or pain in the hands, arms, feet, or legs.
  
• cough or hoarseness.
• diarrhea (severe)
• difficult or labored breathing.
• fever or chills.
• rash (severe)
• sensation of pins and needles.
• stabbing chest pain.

エルロチニブ 上流と下流の製品情報

原材料

準備製品

エルロチニブ 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12470	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	6011	58
shandong perfect biotechnology co.ltd	+86-53169958659; +8618596095638	sales@sdperfect.com	China	294	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9341	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
Hubei XinRunde Chemical Co., Ltd.	+8615102730682	bruce@xrdchem.cn	CHINA	566	55

183321-74-6(エルロチニブ)キーワード:

---

• 183321-74-6
• ERLOTINIB
• ERLOTINIB HCL SALT
• 4-[(3-ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline
• n-(3-ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine
• Erlotinib Hydrochloirde
• 4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-
• ERLOTININ
• N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
• Erlotinib & its intermediates
• CP-358774, Ro 50-8231
• Erlotinib Free Base
• OSI 744
• R 1415
• Erlotinib &aMp
• its interMediates
• O-desmethyl erlotinib carboxylic acid
• Erlotinib N-(3-Ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine
• Erlotinib ERLOTINIB
• Erlotinib (OSI-744)
• Erlonat
• Erlotinib (Tarceva)
• NSC-71878
• OSI744;CP-358774;NSC-71878;ERLOTINIB HCL (OSI 744;CP358774;NSC718781)
• Erlotinib USP/EP/BP
• Erlotinib (OSI744, Tarceva)
• ErlotinibQ: What is Erlotinib Q: What is the CAS Number of Erlotinib Q: What is the storage condition of Erlotinib Q: What are the applications of Erlotinib
• ERLOTINIB HCL
• Tarceva
• Erlortinib
• Erlotinib 183321-74-6
• エルロチニブ
• 4-[(3-エチニルフェニル)アミノ]-6,7-ビス(2-メトキシエトキシ)キナゾリン
• N-(3-エチニルフェニル)-6,7-ビス(2-メトキシエトキシ)キナゾリン-4-アミン
• 4-(3-エチニルフェニルアミノ)-6,7-ビス(2-メトキシエトキシ)キナゾリン
• 4-(3-エチニルフェニルアミノ)-6,7-ビス(3-オキサブタン-1-イルオキシ)キナゾリン
• N-(3-エチニルフェニル)-6,7-ビス(2-メトキシエトキシ)-4-キナゾリンアミン