3-(4-Pyridyl)indole suppliers
3-(4-Pyridyl)indole
- CAS:
- 7272-84-6
- MF:
- C13H10N2
- MW:
- 194.23
Suppliers by country/region
Properties
- storage temp.
- +2C to +8C
- solubility
- DMSO, Methanol
- form
- Yellow solid
- color
- Yellow
- Stability:
- Light Sensitive
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302+H312+H332
- Precautionary statements
- P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P321-P330-P362+P364-P501
Use
Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. 3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 μM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay. It also inhibits ROCK-II and PRK2, another Rho-dependent kinase, with similar potency, while inhibiting MSK-1 and PKA with relatively weaker potency.[Cayman Chemical]
41 supplier list of "3-(4-Pyridyl)indole"
$0.37/ 1g
- Product Name:3-(4-Pyridyl)indole
- Products Intro:Purity: 99%|Package: 1g;0.37USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:RhoKinaseInhibitorIII,Rockout-CAS7272-84-6-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:555553 | Purity:TheRhoKinaseInhibitorIII,Rockout,alsoreferencedunderCAS7272-84-6,controlsthebiol
- Company Type: Trader
- Country/Region: INDIA
- Product Name:3-(4-pyridinyl)-1H-Indole
- Products Intro:Brand:ACCEL | Product Number:DQ2855 | Purity:97.00%
- Company Type: Trader
- Country/Region: UNITED STATES