Sarpogrelate hydrochloride manufacturers and suppliers

Sarpogrelate hydrochloride suppliers

Properties

Melting point:: 145-148°C

storage temp.: Inert atmosphere,2-8°C

solubility: deionized water: ≥5mg/mL

form: solid

InChIKey: POQBIDFFYCYHOB-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS07,GHS09

Signal word: Warning

Hazard statements: H302-H400

Precautionary statements: P273

Hazard Codes: Xn,N

Risk Statements: 22-50/53

Safety Statements: 60-61

RIDADR: UN 3077 9 / PGIII

WGK Germany: 3

Use

Sarpogrelate hydrochloride, a potent and selective serotonin 5-HT2 receptor antagonist, was launched in Japan as an antithrombotic. It exhibits inhibition of ex vivo platelet aggregation stimulated by serotonin in combination with collagen and suppression of blood vessel constriction mediated by 5-HT2 in vitro. Its antithrombotic effects have been demonstrated in several in vivo experimental models including reduction of the mortality rate in acute pulmonary thromboembolic disease, arterial thrombosis, and peripheral obstructive disease. Sarpogrelate has been shown to be especially useful as an antiplatelet agent for patients with Type 2 diabetes mellitus, in whom 5-HT2mediated amplification of collageninduced platelet aggregation is significantly increased.

You can find Sarpogrelate hydrochloride suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.