Ziprasidone suppliers
Ziprasidone
- CAS:
- 146939-27-7
- MF:
- C21H21ClN4OS
- MW:
- 412.94
Suppliers by country/region
Company Type
Properties
- Melting point:
- 213-215°C
- Boiling point:
- 554.8±50.0 °C(Predicted)
- Density
- 1.369±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.34±0.20(Predicted)
- color
- Brown to Dark Brown
- Merck
- 14,10171
Safety Information
- Symbol(GHS)
GHS07,GHS08
- Signal word
- Warning
- Hazard statements
- H317-H373
- Precautionary statements
- P260-P272-P280-P302+P352-P314-P333+P313
- Hazard Codes
- F,T
- Risk Statements
- 60-61-11-19-38
- Safety Statements
- 53-45
- RTECS
- NM3241000
- HS Code
- 2934.20.8000
Use
Ziprasidone, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one, is available as the hydrochloride monohydrate for oral administration (Geodon) and as the mesylate trihydrate saltfor intramuscular (IM) injection. The compound is well absorbedwith peak plasma levels occurring at 6 to 8 hours afteroral administration. The oral absorption is enhanced approximatelytwofold in the presence of food. Ziprasidone isbound about 99% to plasma proteins, primarily to albuminand α1-acid glycoprotein. Ziprasidone is not displaced in thepresence of two highly protein bound drugs, warfarin andpropranolol. Ziprasidone is extensively metabolized withonly about 5 % of the drug excreted unchanged.23 In humans,two major pathways are responsible for the metabolism ofziprasidone: (a) oxidation by CYP3A4 (one third) and (b) reductionby aldehyde oxidase (two thirds).The combinedaction of these metabolic pathways leads to four majorcirculating metabolites: benzisothiazole piperazine sulfoxide(BITP-sulfoxide), benzisothiazole piperazine sulfone (BITPsulfone),ziprasidone sulfoxide, and S-methyldihydroziprasidone.
167 supplier list of "Ziprasidone"
$1.00-0.50 / 1kg
- Product Name:Ziprasidone
- Products Intro:Purity: 99% | Package: 1kg;1USD|2kg;0.5USD
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: Apixaban intermediates,Selpercatinib(LOXO-292),Ritlecitinib,Elacestrant,Lurasidone intermediates
$1.00/ 1KG
- Product Name:Ziprasidone
- Products Intro:Purity: 98% | Package: 1KG;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$1.10/ 1g
- Product Name:Ziprasidone
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA
$1910.00/ 1Kg/Bag
- Product Name:Ziprasidone
- Products Intro:Purity: 99% | Package: 1Kg/Bag;1910USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: API(Active Pharmaceutical Ingredient),Lab Fine Chemical,Phytochemistry,Cosmetic Raw Materials