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ChemicalBook >> CAS DataBase List >> β-Nicotinamide Mononucleotide

β-Nicotinamide Mononucleotide

β-Nicotinamide Mononucleotide price.
  • $7 - $2194.5
  • Product name: β-Nicotinamide Mononucleotide
  • CAS: 1094-61-7
  • MF: C11H15N2O8P
  • MW: 334.22
  • EINECS:214-136-5
  • MDL Number:MFCD00038748
  • Synonyms:3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium ;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE;1-[3,4-dihydroxy-5-[(hydroxy-oxido-phosphoryl)oxymethyl]oxolan-2-yl]pyridine-5-carboxamide;β-Nicotinamide ribose monophosphate, β-NMN, Nicotinamide ribotide, NMN, Nicotinamide-1-ium-1-β-D-ribofuranoside 5μ-phosphate;1-Deoxy-1-(3-carbamoylpyridinio)-5-O-oxylatophosphonyl-β-D-ribofuranose;Nicotinamide ribonucleoside 5'-phosphate;β-D-NMN;3-(AMinocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridiniuM Inner Salt
66 prices
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  • AHH
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  • American Custom Chemicals Corporation
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  • 2.5MG
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  • 1g
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  • ManufacturerAHH
  • Product numberMT-19651
  • Product descriptionbeta-Nicotinamidemononucleotide 98%
  • Packaging0.25g
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1094617
  • Product descriptionbeta-Nicotinamidemononucleotide
  • Packaging1g
  • Price$180.25
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number1094617
  • Product descriptionbeta-Nicotinamidemononucleotide
  • Packaging5g
  • Price$514.8
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number1094617
  • Product descriptionbeta-Nicotinamidemononucleotide
  • Packaging10g
  • Price$883.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA315149
  • Product description((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97%
  • Packaging100mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA315149
  • Product description((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97%
  • Packaging250mg
  • Price$11
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA315149
  • Product description((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97%
  • Packaging1g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA315149
  • Product description((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97%
  • Packaging5g
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA315149
  • Product description((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97%
  • Packaging10g
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA315149
  • Product description((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97%
  • Packaging25g
  • Price$237
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0002776
  • Product descriptionBETA-NICOTINAMIDE MONONUCLEOTIDE 95.00%
  • Packaging2.5MG
  • Price$742.5
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0002776
  • Product descriptionBETA-NICOTINAMIDE MONONUCLEOTIDE 95.00%
  • Packaging25MG
  • Price$2194.5
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIB3016
  • Product descriptionb-Nicotinamide mononucleotide
  • Packaging250mg
  • Price$82
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIB3016
  • Product descriptionb-Nicotinamide mononucleotide
  • Packaging1g
  • Price$176
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS013745
  • Product description((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97%
  • Packaging100mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY129470
  • Product description3-(Aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridiniumInnerSalt ≥97%
  • Packaging250mg
  • Price$10
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-19651 beta-Nicotinamidemononucleotide 98% 0.25g $300 2021-12-16 Buy
Alichem 1094617 beta-Nicotinamidemononucleotide 1g $180.25 2021-12-16 Buy
Alichem 1094617 beta-Nicotinamidemononucleotide 5g $514.8 2021-12-16 Buy
Alichem 1094617 beta-Nicotinamidemononucleotide 10g $883.75 2021-12-16 Buy
Ambeed A315149 ((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97% 100mg $7 2021-12-16 Buy
Ambeed A315149 ((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97% 250mg $11 2021-12-16 Buy
Ambeed A315149 ((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97% 1g $14 2021-12-16 Buy
Ambeed A315149 ((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97% 5g $56 2021-12-16 Buy
Ambeed A315149 ((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97% 10g $105 2021-12-16 Buy
Ambeed A315149 ((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97% 25g $237 2021-12-16 Buy
American Custom Chemicals Corporation NUC0002776 BETA-NICOTINAMIDE MONONUCLEOTIDE 95.00% 2.5MG $742.5 2021-12-16 Buy
American Custom Chemicals Corporation NUC0002776 BETA-NICOTINAMIDE MONONUCLEOTIDE 95.00% 25MG $2194.5 2021-12-16 Buy
Apolloscientific BIB3016 b-Nicotinamide mononucleotide 250mg $82 2021-12-16 Buy
Apolloscientific BIB3016 b-Nicotinamide mononucleotide 1g $176 2021-12-16 Buy
Arctom AS013745 ((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylhydrogenphosphate 97% 100mg $7 2021-12-16 Buy
Arctom SY129470 3-(Aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridiniumInnerSalt ≥97% 250mg $10 2021-12-16 Buy

Properties

Melting point :166 °C(dec.)
storage temp. :-20°C
solubility :DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
form :Solid
color :White to Yellow
Merck :13,6697
BRN :3570187
Stability :Very Hygroscopic
InChI :InChI=1/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/s3
InChIKey :DAYLJWODMCOQEW-TURQNECASA-N
SMILES :O[C@@H]1[C@@H]([C@@H](COP(O)([O-])=O)O[C@H]1[N+]1=CC=CC(C(=O)N)=C1)O |&1:1,2,3,11,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

β-Nicotinamide mononucleotide (β-NMN) is an intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+; ). Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to generate β-NMN, which is subsequently converted to NAD+ by β-NMN adenyltransferase. At 50-100 μM, β-NMN has been used to enhance NAD biosynthesis and glucose-stimulated insulin secretion in a Nampt+/- mouse model of metabolic disease, demonstrating a role for Nampt in β cell function. Furthermore, at 500 mg/kg/day, it has been shown to ameliorate glucose intolerance in high-fat diet-induced type 2 diabetes mice by restoring NAD+ levels.

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