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ChemicalBook >> CAS DataBase List >> (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride price.
  • $20 - $1350
  • Product name: (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
  • CAS: 1448189-80-7
  • MF: C22H31ClN4O3S
  • MW: 467.03
  • EINECS:604-604-1
  • MDL Number:
  • Synonyms:(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride;Protein degrader 1 (hydrochloride);(S,R,S)-AHPC hydrochloride;MDK-7526;ULM-1;(4R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide hydrochloride;Protein degrader 1;141003;(2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide hydrochloride
Price25 Properties Safety Information Description
25 prices
Selected condition：
Brand
  • Abosyn
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • BroadPharm
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Iris Biotech GmbH
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 2g
  • 5g
  • ManufacturerAbosyn
  • Product number10-3468
  • Product description(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 95%-98%
  • Packaging1g
  • Price$695
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number5959EF
  • Product descriptionProteindegrader1hydrochloride
  • Packaging1g
  • Price$998
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113059
  • Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
  • Packaging5mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113059
  • Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
  • Packaging25mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113059
  • Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
  • Packaging50mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113059
  • Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
  • Packaging100mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113059
  • Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
  • Packaging250mg
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113059
  • Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
  • Packaging1g
  • Price$272
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA113059
  • Product description(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98%
  • Packaging5g
  • Price$992
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0005701
  • Product description(2S,4R)-1-((S)-2-AMINO-3,3-DIMETHYLBUTANOYL)-4-HYDROXY-N-(4-(4-METHYLTHIAZOL-5-YL)BENZYL)PYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$456.82
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-24441
  • Product descriptionVHLLigand1HClsalt 98%
  • Packaging250mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21591
  • Product descriptionVHL Ligand 1 (hydrochloride) ≥95%
  • Packaging10mg
  • Price$72
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21591
  • Product descriptionVHL Ligand 1 (hydrochloride) ≥95%
  • Packaging25mg
  • Price$151
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21591
  • Product descriptionVHL Ligand 1 (hydrochloride) ≥95%
  • Packaging50mg
  • Price$249
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21591
  • Product descriptionVHL Ligand 1 (hydrochloride) ≥95%
  • Packaging100mg
  • Price$353
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM328305
  • Product description(2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;hydrochloride 95%+
  • Packaging500mg
  • Price$96
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 10-3468 (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 95%-98% 1g $695 2021-12-16 Buy
AK Scientific 5959EF Proteindegrader1hydrochloride 1g $998 2021-12-16 Buy
Ambeed A113059 (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98% 5mg $20 2021-12-16 Buy
Ambeed A113059 (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98% 25mg $37 2021-12-16 Buy
Ambeed A113059 (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98% 50mg $49 2021-12-16 Buy
Ambeed A113059 (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98% 100mg $73 2021-12-16 Buy
Ambeed A113059 (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98% 250mg $109 2021-12-16 Buy
Ambeed A113059 (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98% 1g $272 2021-12-16 Buy
Ambeed A113059 (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamidehydrochloride 98% 5g $992 2021-12-16 Buy
American Custom Chemicals Corporation INB0005701 (2S,4R)-1-((S)-2-AMINO-3,3-DIMETHYLBUTANOYL)-4-HYDROXY-N-(4-(4-METHYLTHIAZOL-5-YL)BENZYL)PYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE 95.00% 5MG $456.82 2021-12-16 Buy
BroadPharm BP-24441 VHLLigand1HClsalt 98% 250mg $180 2021-12-16 Buy
Cayman Chemical 21591 VHL Ligand 1 (hydrochloride) ≥95% 10mg $72 2024-03-01 Buy
Cayman Chemical 21591 VHL Ligand 1 (hydrochloride) ≥95% 25mg $151 2024-03-01 Buy
Cayman Chemical 21591 VHL Ligand 1 (hydrochloride) ≥95% 50mg $249 2024-03-01 Buy
Cayman Chemical 21591 VHL Ligand 1 (hydrochloride) ≥95% 100mg $353 2024-03-01 Buy
Chemenu CM328305 (2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide;hydrochloride 95%+ 500mg $96 2021-12-16 Buy
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Properties

storage temp. :2-8°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
form :A crystalline solid
InChIKey :JYRTWGCWUBURGU-XIMRXPCLNA-N
SMILES :C([C@@H]1C[C@@H](O)CN1C(=O)[C@@H](N)C(C)(C)C)(=O)NCC1C=CC(C2=C(N=CS2)C)=CC=1.Cl |&1:1,3,9,r|

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

VHL ligand 1 is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs). It is the von Hippel-Lindau (VHL) E3 ligase binding portion of some VHL-based PROTACs, including BET PROTAC MZ1 (Item No. 21622).

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Suppliers and manufacturers

Zhengzhou Anbu Chem Co.,Ltd
(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
$0.00 /1KG
(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride CAS:1448189-80-7
Suzhou Origin Specialty Chemicals Co., Ltd.
Shanghai finete Pharmaceutical Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Jinan Carbotang Biotech Co.,Ltd.
Accela ChemBio Inc.
Shochem(Shanghai) Co.,Ltd
BOC Sciences
Neostar United (Changzhou) Industrial Co., Ltd.
Career Henan Chemica Co