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ChemicalBook >> CAS DataBase List >> E-7449

E-7449

E-7449 price.
  • $32 - $2250
  • Product name: E-7449
  • CAS: 1140964-99-3
  • MF: C18H15N5O
  • MW: 317.34
  • EINECS:
  • MDL Number:MFCD28167842
  • Synonyms:E7449;E-7449;8-(1,3-dihydro-isoindol-2-ylmethyl)-2,9-dihydro-1,2,7,9-tetraaza-phenalen-3-one;E7449;E 7449;3H-Pyridazino[3,4,5-de]quinazolin-3-one, 8-[(1,3-dihydro-2H-isoindol-2-yl)methyl]-1,2-dihydro-;UNII-9X5A2QIA7C;Stenoparib (E7449);E7449,PARP,Inhibitor,inhibit,E 7449,E-7449,poly ADP ribose polymerase
Price22 Properties Safety Information Description
22 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • Manufactureraablocks
  • Product numberAA000AHB
  • Product descriptionE-7449 97%
  • Packaging1mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA000AHB
  • Product descriptionE-7449 97%
  • Packaging5mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA000AHB
  • Product descriptionE-7449 97%
  • Packaging10mg
  • Price$315
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA000AHB
  • Product descriptionE-7449 97%
  • Packaging25mg
  • Price$595
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA000AHB
  • Product descriptionE-7449 97%
  • Packaging50mg
  • Price$1035
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA000AHB
  • Product descriptionE-7449 97%
  • Packaging100mg
  • Price$1835
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3226EM
  • Product description3H-Pyridazino(3,4,5-de)quinazolin-3-one,8-((1,3-dihydro-2H-isoindol-2-yl)methyl)-1,2-dihydro-
  • Packaging25mg
  • Price$733
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21658
  • Product descriptionE7449 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21658
  • Product descriptionE7449 ≥98%
  • Packaging5mg
  • Price$145
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21658
  • Product descriptionE7449 ≥98%
  • Packaging10mg
  • Price$275
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21658
  • Product descriptionE7449 ≥98%
  • Packaging25mg
  • Price$571
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3479
  • Product descriptionE7449 >99.0%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3479
  • Product descriptionE7449 >99.0%
  • Packaging10mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3479
  • Product descriptionE7449 >99.0%
  • Packaging50mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3479
  • Product descriptionE7449 >99.0%
  • Packaging100mg
  • Price$1620
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004485
  • Product descriptionE7449 98+%
  • Packaging5mg
  • Price$525
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000AHB E-7449 97% 1mg $82 2021-12-16 Buy
aablocks AA000AHB E-7449 97% 5mg $195 2021-12-16 Buy
aablocks AA000AHB E-7449 97% 10mg $315 2021-12-16 Buy
aablocks AA000AHB E-7449 97% 25mg $595 2021-12-16 Buy
aablocks AA000AHB E-7449 97% 50mg $1035 2021-12-16 Buy
aablocks AA000AHB E-7449 97% 100mg $1835 2021-12-16 Buy
AK Scientific 3226EM 3H-Pyridazino(3,4,5-de)quinazolin-3-one,8-((1,3-dihydro-2H-isoindol-2-yl)methyl)-1,2-dihydro- 25mg $733 2021-12-16 Buy
Cayman Chemical 21658 E7449 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 21658 E7449 ≥98% 5mg $145 2024-03-01 Buy
Cayman Chemical 21658 E7449 ≥98% 10mg $275 2024-03-01 Buy
Cayman Chemical 21658 E7449 ≥98% 25mg $571 2024-03-01 Buy
ChemScene CS-3479 E7449 >99.0% 5mg $144 2021-12-16 Buy
ChemScene CS-3479 E7449 >99.0% 10mg $252 2021-12-16 Buy
ChemScene CS-3479 E7449 >99.0% 50mg $900 2021-12-16 Buy
ChemScene CS-3479 E7449 >99.0% 100mg $1620 2021-12-16 Buy
Crysdot CD31004485 E7449 98+% 5mg $525 2021-12-16 Buy
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Properties

Density :1.53±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:0.2(Max Conc. mg/mL);0.63(Max Conc. mM)
form :A crystalline solid
pka :9.51±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

E 7449 is a dual inhibitor of PARP1/2 and tankyrase1/2 exhibits anti-tumor activity in BRCA-deficient in vivo models. PARP1/2 and tankyrase1/2 are involved with DNA damage and canonical Wnt/β-catenin signaling, respectively.

Suppliers and manufacturers

ATK CHEMICAL COMPANY LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
LEAPCHEM CO., LTD.
Aladdin Scientific
Amadis Chemical Company Limited Chengdu Henghui Pharm Tec Co. Ltd.