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ChemicalBook >> CAS DataBase List >> F16

F16

F16 price.
  • $14 - $499.33
  • Product name: F16
  • CAS: 36098-33-6
  • MF: C16H15IN2
  • MW: 362.21
  • EINECS:
  • MDL Number:MFCD00050298
  • Synonyms:F16;4-[(1E)-2-(1H-INDOL-3-YL)ETHENYL]-1-METHYL-PYRIDINIUM IODIDE;4-[(E)-2-(INDOL-3-YL)ETHENYL]-N-METHYLPYRIDINIUM IODIDE;F-16;COMPOUND F16;Compound F16);F16 (F-16;3-[2-(1-methylpyridin-1-ium-4-yl)ethenyl]-1H-indole,iodide;F16/Cell proliferation inhibitor (F16)
14 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number1730DB
  • Product description3-[2-(1-Methylpyridin-1-ium-4-yl)ethenyl]-1H-indole;iodide
  • Packaging5mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0150226
  • Product description4-((1E)-2-(1H-INDOL-3-YL)ETHENYL)-1-METHYL-PYRIDINIUM IODIDE 95.00%
  • Packaging5MG
  • Price$499.33
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5565
  • Product descriptionF16
  • Packaging10mg
  • Price$101
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5565
  • Product descriptionF16
  • Packaging50mg
  • Price$437
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611748
  • Product descriptionF16
  • Packaging25mg
  • Price$229.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611748
  • Product descriptionF16
  • Packaging50mg
  • Price$382.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10022
  • Product descriptionF16 ≥98%
  • Packaging1mg
  • Price$14
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10022
  • Product descriptionF16 ≥98%
  • Packaging5mg
  • Price$53
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10022
  • Product descriptionF16 ≥98%
  • Packaging10mg
  • Price$89
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10022
  • Product descriptionF16 ≥98%
  • Packaging50mg
  • Price$384
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002103
  • Product descriptionF16 98+%
  • Packaging25mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002103
  • Product descriptionF16 98+%
  • Packaging50mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC23973
  • Product descriptionF16 >98%
  • Packaging50mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberF118805
  • Product descriptionF16
  • Packaging25mg
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1730DB 3-[2-(1-Methylpyridin-1-ium-4-yl)ethenyl]-1H-indole;iodide 5mg $155 2021-12-16 Buy
American Custom Chemicals Corporation CHM0150226 4-((1E)-2-(1H-INDOL-3-YL)ETHENYL)-1-METHYL-PYRIDINIUM IODIDE 95.00% 5MG $499.33 2021-12-16 Buy
ApexBio Technology C5565 F16 10mg $101 2021-12-16 Buy
ApexBio Technology C5565 F16 50mg $437 2021-12-16 Buy
Biorbyt Ltd orb611748 F16 25mg $229.5 2021-12-16 Buy
Biorbyt Ltd orb611748 F16 50mg $382.5 2021-12-16 Buy
Cayman Chemical 10022 F16 ≥98% 1mg $14 2024-03-01 Buy
Cayman Chemical 10022 F16 ≥98% 5mg $53 2024-03-01 Buy
Cayman Chemical 10022 F16 ≥98% 10mg $89 2024-03-01 Buy
Cayman Chemical 10022 F16 ≥98% 50mg $384 2024-03-01 Buy
Crysdot CD31002103 F16 98+% 25mg $76 2021-12-16 Buy
Crysdot CD31002103 F16 98+% 50mg $132 2021-12-16 Buy
DC Chemicals DC23973 F16 >98% 50mg $144 2021-12-16 Buy
TRC F118805 F16 25mg $95 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :≤500μg/ml in ethanol;20mg/ml in DMSO;25mg/ml in dimethyl formamide
form :Orange solid.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

F16 is a small, cationic, lipophilic molecule which binds preferentially to mitochondrial membranes and disrupts their function. F16 was discovered in high throughput screens for tumor inhibitors, where it was found to induce apoptosis in HER-1/EGFR-expressing breast carcinoma cell lines. In addition to being a potential antitumor agent, F16 is an easily visualized fluorescent molecule which can also be used to visualize mitochondria under confocal microscopy. The mechanism of apoptosis induction by F16 is believed to be through disruption of the mitochondrial transmembrane potential.

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