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ChemicalBook >> CAS DataBase List >> JASPLAKINOLIDE

JASPLAKINOLIDE

JASPLAKINOLIDE price.
  • $169 - $750
  • Product name: JASPLAKINOLIDE
  • CAS: 102396-24-7
  • MF: C36H45BrN4O6
  • MW: 709.67
  • EINECS:
  • MDL Number:MFCD00873735
  • Synonyms:JASPLAKINOLIDE;JASPLAKINOLIDE, JASPIS JOHNSTONI;(3S,6R,9R,13S,15R,16E,19S)-3,5,13,15,17,19-Hexamethyl-6-[(2-bromo-1H-indole-3-yl)methyl]-9-(4-hydroxyphenyl)-12-oxa-2,5,8-triazacyclononadeca-16-ene-1,4,7,11-tetraone;[3S,6R,9R,13S,15R,19S,16E,(+)]-6-[(2-Bromo-1H-indol-3-yl)methyl]-9-(4-hydroxyphenyl)-3,5,13,15,17,19-hexamethyl-2,5,8-triaza-12-oxacyclononadecan-16-ene-1,4,7,11-tetrone;NSC 613009;Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem;Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl];GQWYWHOHRVVHAP-DHKPLNAMSA-N
12 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50ug
  • 50μg
  • 100ug
  • 100μg
  • 100U
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0037-C100
  • Product descriptionJasplakinolide(highpurity) ≥98%(HPLC)
  • Packaging100μg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7189
  • Product descriptionJasplakinolide
  • Packaging50ug
  • Price$229
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7189
  • Product descriptionJasplakinolide
  • Packaging100ug
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11705
  • Product descriptionJasplakinolide ≥98%
  • Packaging50μg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11705
  • Product descriptionJasplakinolide ≥98%
  • Packaging100μg
  • Price$287
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012978
  • Product descriptionJasplakinolide ≥98.0%
  • Packaging100ug
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberJ4580
  • Product descriptionJasplakinolide ≥97% (HPLC)
  • Packaging100μg
  • Price$740
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2792
  • Product descriptionJasplakinolide ≥97%(HPLC)
  • Packaging100U
  • Price$374
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberJ210700
  • Product descriptionJasplakinolide
  • Packaging100μg
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number044973
  • Product descriptionJasplakinolide
  • Packaging50ug
  • Price$392
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number164561
  • Product descriptionJasplakinolide
  • Packaging50ug
  • Price$418
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255548
  • Product descriptionJasplakinolide
  • Packaging100ug
  • Price$631
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0037-C100 Jasplakinolide(highpurity) ≥98%(HPLC) 100μg $280 2021-12-16 Buy
ApexBio Technology B7189 Jasplakinolide 50ug $229 2021-12-16 Buy
ApexBio Technology B7189 Jasplakinolide 100ug $390 2021-12-16 Buy
Cayman Chemical 11705 Jasplakinolide ≥98% 50μg $169 2024-03-01 Buy
Cayman Chemical 11705 Jasplakinolide ≥98% 100μg $287 2024-03-01 Buy
ChemScene CS-0012978 Jasplakinolide ≥98.0% 100ug $750 2021-12-16 Buy
Sigma-Aldrich J4580 Jasplakinolide ≥97% (HPLC) 100μg $740 2024-03-01 Buy
Tocris 2792 Jasplakinolide ≥97%(HPLC) 100U $374 2021-12-16 Buy
TRC J210700 Jasplakinolide 100μg $235 2021-12-16 Buy
Usbiological 044973 Jasplakinolide 50ug $392 2021-12-16 Buy
Usbiological 164561 Jasplakinolide 50ug $418 2021-12-16 Buy
Usbiological 255548 Jasplakinolide 100ug $631 2021-12-16 Buy

Properties

Melting point :110℃ (decomposition)
storage temp. :-20°C
solubility :DMSO: >2mg/mL
form :Off-white solid
color :off white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

Jasplakinolide is a natural macrocyclic peptide first isolated from a marine sponge. It potently inhibits the proliferation of PC3 prostate carcinoma cells (IC50 = 35 nM) by binding F-actin (KD = 15 nM). This binding of jasplakinolide to actin, which is competitive with phalloidin, stabilizes actin filaments in vitro but disrupts actin filaments and induces irregular polymerization of monomeric actin in vivo. This compound is used to investigate the role of actin in diverse cellular roles, such as motility, transport, and development.

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