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ChemicalBook >> CAS DataBase List >> L-685 458

L-685 458

L-685 458 price.
  • $152.5 - $2600
  • Product name: L-685 458
  • CAS: 292632-98-5
  • MF: C39H52N4O6
  • MW: 672.85
  • EINECS:
  • MDL Number:MFCD03093402
  • Synonyms:(5S)-(tert-Butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl)-L-leucy-L-phenylalaninamide;N-[(2R,4R,5S)-5-[[(1,1-DiMethylethoxy)carbonyl]aMino]-4-hydroxy-1-oxo-6- phenyl-2-(phenylMethyl)hexyl]-L-leucyl-L-phenylalaninaMide;CS-2367;L-685458 (L-685,458;L-685458;L 685458;L685458;L-Phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl-;Apoptosis,alzheimer’s disease,L 685458,inhibit,L685458,HES1,cancer,Inhibitor,Gamma secretase,γ-secretase,L-685458
Price24 Properties Safety Information Description
24 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 250ug
  • 500ug
  • 1MG
  • 2mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number1682CP
  • Product descriptionl-685,458
  • Packaging10mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA142296
  • Product descriptionL-685458 98%
  • Packaging5mg
  • Price$552
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA142296
  • Product descriptionL-685458 98%
  • Packaging10mg
  • Price$1066
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000845
  • Product descriptionL-685,458 95.00%
  • Packaging1MG
  • Price$774.95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4404
  • Product descriptionL-685,458
  • Packaging5mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT109461
  • Product descriptionL-685458
  • Packaging250ug
  • Price$152.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT109461
  • Product descriptionL-685458
  • Packaging500ug
  • Price$265
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT109461
  • Product descriptionL-685458
  • Packaging1mg
  • Price$459
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT109461
  • Product descriptionL-685458
  • Packaging2mg
  • Price$799
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT109461
  • Product descriptionL-685458
  • Packaging5mg
  • Price$1736.95
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14926
  • Product descriptionL-685,458
  • Packaging1mg
  • Price$183
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14926
  • Product descriptionL-685,458
  • Packaging5mg
  • Price$724
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14926
  • Product descriptionL-685,458
  • Packaging10mg
  • Price$1266
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5258
  • Product descriptionL-685458 99.78%
  • Packaging1mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5258
  • Product descriptionL-685458 99.78%
  • Packaging5mg
  • Price$528
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5258
  • Product descriptionL-685458 99.78%
  • Packaging10mg
  • Price$1008
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1682CP l-685,458 10mg $232 2021-12-16 Buy
Ambeed A142296 L-685458 98% 5mg $552 2021-12-16 Buy
Ambeed A142296 L-685458 98% 10mg $1066 2021-12-16 Buy
American Custom Chemicals Corporation INB0000845 L-685,458 95.00% 1MG $774.95 2021-12-16 Buy
ApexBio Technology A4404 L-685,458 5mg $450 2021-12-16 Buy
Biosynth Carbosynth FT109461 L-685458 250ug $152.5 2021-12-16 Buy
Biosynth Carbosynth FT109461 L-685458 500ug $265 2021-12-16 Buy
Biosynth Carbosynth FT109461 L-685458 1mg $459 2021-12-16 Buy
Biosynth Carbosynth FT109461 L-685458 2mg $799 2021-12-16 Buy
Biosynth Carbosynth FT109461 L-685458 5mg $1736.95 2021-12-16 Buy
Cayman Chemical 14926 L-685,458 1mg $183 2024-03-01 Buy
Cayman Chemical 14926 L-685,458 5mg $724 2024-03-01 Buy
Cayman Chemical 14926 L-685,458 10mg $1266 2024-03-01 Buy
ChemScene CS-5258 L-685458 99.78% 1mg $168 2021-12-16 Buy
ChemScene CS-5258 L-685458 99.78% 5mg $528 2021-12-16 Buy
ChemScene CS-5258 L-685458 99.78% 10mg $1008 2021-12-16 Buy
Next Last

Properties

Melting point :212-213 °C
Boiling point :938.5±65.0 °C(Predicted)
Density :1.155±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >10 mg/mL, soluble
form :solid
pka :12.09±0.46(Predicted)
color :white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

L-685,458 is a potent and selective γ-secretase inhibitor (IC50 = 17 nM) that displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. It exhibits equal potency for inhibition of Aβ40 and Aβ42 peptides.

Suppliers and manufacturers

Alpha Biopharmaceuticals Co., Ltd
ATK CHEMICAL COMPANY LIMITED
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Nextpeptide Inc
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd