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ChemicalBook >> CAS DataBase List >> LSD1-IN-1

LSD1-IN-1

LSD1-IN-1 price.
  • $32 - $2636
  • Product name: LSD1-IN-1
  • CAS: 1431326-61-2
  • MF: C15H24Cl2N2
  • MW: 303.27046
  • EINECS:-0
  • MDL Number:MFCD28900684
  • Synonyms:rel-N1-[(1R,2S)-2-Phenylcyclopropyl]-1,4-cyclohexanediamine hydrochloride (1:2);LSD1-IN-1;ORY-1001;ORY-1001 (RG-6016);ORY-1001 2HCl salt;RG 6016;RG 6016;RG6016;RG-6016;ORY1001;ORY 1001;ORY-1001 trans and cis isomers
Price12 Properties Safety Information Description
12 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 10mM(in 1mL DMSO)
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number2355AQ
  • Product description4-N-[(1R,2S)-2-phenylcyclopropyl]cyclohexane-1,4-diamine;dihydrochloride
  • Packaging250mg
  • Price$2636
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5882
  • Product descriptionORY-1001
  • Packaging10mM(in 1mL DMSO)
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19136
  • Product descriptionORY-1001 ≥98%
  • Packaging500μg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19136
  • Product descriptionORY-1001 ≥98%
  • Packaging1mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19136
  • Product descriptionORY-1001 ≥98%
  • Packaging5mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19136
  • Product descriptionORY-1001 ≥98%
  • Packaging10mg
  • Price$426
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM203679
  • Product descriptionN1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diaminedihydrochloride 95+%
  • Packaging100mg
  • Price$1257
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003513
  • Product descriptionORY-1001 98+%
  • Packaging10mg
  • Price$254
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003513
  • Product descriptionORY-1001 98+%
  • Packaging25mg
  • Price$487
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003513
  • Product descriptionORY-1001 98+%
  • Packaging50mg
  • Price$875
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8541
  • Product descriptionORY-1001(LSD1-IN-1) >98%
  • Packaging250mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberO671003
  • Product descriptionORY-1001
  • Packaging10mg
  • Price$470
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2355AQ 4-N-[(1R,2S)-2-phenylcyclopropyl]cyclohexane-1,4-diamine;dihydrochloride 250mg $2636 2021-12-16 Buy
ApexBio Technology B5882 ORY-1001 10mM(in 1mL DMSO) $140 2021-12-16 Buy
Cayman Chemical 19136 ORY-1001 ≥98% 500μg $32 2024-03-01 Buy
Cayman Chemical 19136 ORY-1001 ≥98% 1mg $61 2024-03-01 Buy
Cayman Chemical 19136 ORY-1001 ≥98% 5mg $230 2024-03-01 Buy
Cayman Chemical 19136 ORY-1001 ≥98% 10mg $426 2024-03-01 Buy
Chemenu CM203679 N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diaminedihydrochloride 95+% 100mg $1257 2021-12-16 Buy
Crysdot CD31003513 ORY-1001 98+% 10mg $254 2021-12-16 Buy
Crysdot CD31003513 ORY-1001 98+% 25mg $487 2021-12-16 Buy
Crysdot CD31003513 ORY-1001 98+% 50mg $875 2021-12-16 Buy
DC Chemicals DC8541 ORY-1001(LSD1-IN-1) >98% 250mg $1000 2021-12-16 Buy
TRC O671003 ORY-1001 10mg $470 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :insoluble in EtOH; ≥23.15 mg/mL in H2O; ≥6.9 mg/mL in DMSO with gentle warming
form :solid
CAS DataBase Reference :1431326-61-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Lysine-specific demethylase 1 (LSD1) demethylates H3K4 and H3K9, resulting in transcriptional repression. It also controls the tumor suppressor activity of p53 by demethylating a specific p53 lysine residue (LYS370). ORY-1001 is an orally available, selective inhibitor of LSD1 (IC50 < 20 nM). It targets acute myeloid leukemia (AML) stem cells and significantly reduces tumor cell load while increasing survival time in mouse models of AML. ORY-1001 is in clinical trials for cancer treatment.

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