MK8245
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- $48 - $1800
- Product name: MK8245
- CAS: 1030612-90-8
- MF: C17H16BrFN6O4
- MW: 467.25
- EINECS:
- MDL Number:MFCD20039622
- Synonyms:5-[3-[4-(2-Bromo-5-fluorophenoxy)-1-piperidinyl]-5-isoxazolyl]-2H-tetrazole-2-acetic acid;2-(5-(3-(4-(2-broMo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid;MK 8245;MK8245;MK8245;MK-8245;MK 8245;CS-1662;]-2H-tetrazoL;]-5-isoxazoL;5-[3-[4-(2-Bromo-5-fL
29 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberY0300
- Product descriptionMK-8245
- Packaging10mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA515360
- Product descriptionMk-8245 98%
- Packaging2mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA515360
- Product descriptionMk-8245 98%
- Packaging5mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA515360
- Product descriptionMk-8245 98%
- Packaging10mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA515360
- Product descriptionMk-8245 98%
- Packaging25mg
- Price$241
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA515360
- Product descriptionMk-8245 98%
- Packaging50mg
- Price$313
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0006864
- Product descriptionMK-8245 95.00%
- Packaging5MG
- Price$343.2
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4345
- Product descriptionMK-8245
- Packaging50mg
- Price$749
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29421
- Product descriptionMK-8245
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29421
- Product descriptionMK-8245
- Packaging5mg
- Price$268
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29421
- Product descriptionMK-8245
- Packaging10mg
- Price$435
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29421
- Product descriptionMK-8245
- Packaging25mg
- Price$836
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0410
- Product descriptionMK-8245 99.82%
- Packaging2mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0410
- Product descriptionMK-8245 99.82%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0410
- Product descriptionMK-8245 99.82%
- Packaging10mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0410
- Product descriptionMK-8245 99.82%
- Packaging50mg
- Price$540
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y0300 | MK-8245 | 10mg | $288 | 2021-12-16 | Buy |
| Ambeed | A515360 | Mk-8245 98% | 2mg | $48 | 2021-12-16 | Buy |
| Ambeed | A515360 | Mk-8245 98% | 5mg | $95 | 2021-12-16 | Buy |
| Ambeed | A515360 | Mk-8245 98% | 10mg | $142 | 2021-12-16 | Buy |
| Ambeed | A515360 | Mk-8245 98% | 25mg | $241 | 2021-12-16 | Buy |
| Ambeed | A515360 | Mk-8245 98% | 50mg | $313 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0006864 | MK-8245 95.00% | 5MG | $343.2 | 2021-12-16 | Buy |
| ApexBio Technology | A4345 | MK-8245 | 50mg | $749 | 2021-12-16 | Buy |
| Cayman Chemical | 29421 | MK-8245 | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 29421 | MK-8245 | 5mg | $268 | 2024-03-01 | Buy |
| Cayman Chemical | 29421 | MK-8245 | 10mg | $435 | 2024-03-01 | Buy |
| Cayman Chemical | 29421 | MK-8245 | 25mg | $836 | 2024-03-01 | Buy |
| ChemScene | CS-0410 | MK-8245 99.82% | 2mg | $70 | 2021-12-16 | Buy |
| ChemScene | CS-0410 | MK-8245 99.82% | 5mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-0410 | MK-8245 99.82% | 10mg | $190 | 2021-12-16 | Buy |
| ChemScene | CS-0410 | MK-8245 99.82% | 50mg | $540 | 2021-12-16 | Buy |
Properties
Boiling point :698.3±65.0 °C(Predicted)
Density :1.82
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥23.35 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :2.85±0.10(Predicted)
Density :1.82
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥23.35 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :2.85±0.10(Predicted)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
MK-8245 is a liver-targeted inhibitor of stearoyl-CoA desaturase (SCD; IC50s = 3, 3, and 1 nM for rat, mouse, and human SCD1, respectively). It is selective for SCD1 over Δ5- and Δ6-desaturases (IC50s = >100,000 nM). MK-8245 (20-60 mg/kg) reduces the hepatic, but not Harderian gland, ratio of oleic acid to stearic acid, a marker of chronic SCD activity, and blood glucose levels, without inducing the formation of skin lesions or eye squinting behavior, in a mouse model of high-fat diet-induced obesity. It also inhibits hepatitis C virus (HCV) replication without inducing cytotoxicity in LucNeo2 cells (IC50 = 39.8 nM).Related product price
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