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ChemicalBook >> CAS DataBase List >> Montelukast sodium

Montelukast sodium

Montelukast sodium price.
  • $8 - $1880
  • Product name: Montelukast sodium
  • CAS: 151767-02-1
  • MF: C35H37ClNNaO3S
  • MW: 610.18
  • EINECS:604-813-7
  • MDL Number:MFCD00931431
  • Synonyms:montelucast-d6;Montelukast Soudium Tablets;Montelukast sodium ,99%;1-[1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-Methylethyl)phenyl]propyl]thio]Methyl]cyclopropaneacetic Acid SodiuM Salt;Montelukast SoudiuM;MONTELUKST SODIUM;MONTELUKAST SODIUM;MK-476, Singulair
51 prices
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Brand
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
Package
  • y0001435
  • y0001434
  • 10mg
  • 25MG
  • 50mg
  • 50
  • 10
  • 0.1g
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 10g
  • 25g
  • ManufacturerAHH
  • Product numberAPI-1753
  • Product descriptionMontelukast Sodium 98%
  • Packaging0.1g
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberE117
  • Product descriptionMontelukast Sodium
  • Packaging100mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2561AH
  • Product descriptionMontelukast Sodium Hydrate
  • Packaging1g
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232574
  • Product descriptionSodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+%
  • Packaging50mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232574
  • Product descriptionSodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+%
  • Packaging100mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232574
  • Product descriptionSodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+%
  • Packaging250mg
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232574
  • Product descriptionSodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+%
  • Packaging1g
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232574
  • Product descriptionSodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+%
  • Packaging5g
  • Price$227
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA232574
  • Product descriptionSodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+%
  • Packaging25g
  • Price$755
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003425
  • Product descriptionMONTELUKAST SODIUM 95.00%
  • Packaging25MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003425
  • Product descriptionMONTELUKAST SODIUM 95.00%
  • Packaging250MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1792
  • Product descriptionMontelukast Sodium
  • Packaging100mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS486837
  • Product descriptionMontelukast Sodium ≥98%
  • Packaging50mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS486837
  • Product descriptionMontelukast Sodium ≥98%
  • Packaging100mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS486837
  • Product descriptionMontelukast Sodium ≥98%
  • Packaging250mg
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS486837
  • Product descriptionMontelukast Sodium ≥98%
  • Packaging1g
  • Price$55
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1753 Montelukast Sodium 98% 0.1g $420 2021-12-16 Buy
AK Scientific E117 Montelukast Sodium 100mg $54 2021-12-16 Buy
AK Scientific 2561AH Montelukast Sodium Hydrate 1g $124 2021-12-16 Buy
Ambeed A232574 Sodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+% 50mg $8 2021-12-16 Buy
Ambeed A232574 Sodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+% 100mg $15 2021-12-16 Buy
Ambeed A232574 Sodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+% 250mg $21 2021-12-16 Buy
Ambeed A232574 Sodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+% 1g $56 2021-12-16 Buy
Ambeed A232574 Sodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+% 5g $227 2021-12-16 Buy
Ambeed A232574 Sodium(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate 98+% 25g $755 2021-12-16 Buy
American Custom Chemicals Corporation API0003425 MONTELUKAST SODIUM 95.00% 25MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation API0003425 MONTELUKAST SODIUM 95.00% 250MG $1871.1 2021-12-16 Buy
ApexBio Technology B1792 Montelukast Sodium 100mg $116 2021-12-16 Buy
Arctom AS486837 Montelukast Sodium ≥98% 50mg $8 2021-12-16 Buy
Arctom AS486837 Montelukast Sodium ≥98% 100mg $15 2021-12-16 Buy
Arctom AS486837 Montelukast Sodium ≥98% 250mg $21 2021-12-16 Buy
Arctom AS486837 Montelukast Sodium ≥98% 1g $55 2021-12-16 Buy

Properties

Melting point :115 °C(dec.)
storage temp. :2-8°C
solubility :DMSO: ≥8mg/mL at 60°C
form :powder
color :white to tan
optical activity :[α]/D +90 to +106° in methanol (c=1)
Merck :14,6258
BCS Class :1
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, distilled water, or ethanol may be stored at -20°C for up to 1 month.
InChIKey :LBFBRXGCXUHRJY-HKHDRNBDSA-M

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Montelukast was launched as Singulair in Mexico and Finland for the management of mild to moderate asthma inadequately controlled by inhaled corticosteroids and short-acting beta2-agonists. Montelukast can be obtained by an seven-step synthesis from 3-[2(E)-(7-chloroquinolin-2-yl)vinyl] benzaldehyde. Montelukast is a potent, selective and orally active antagonist of the CysLT1 (formerly called LTD4) receptor, thus blocking the effects of the cysteinyl leukotrienes LTC4, LTD4 and LTE4 on microvascular permeability and the activation of eosinophils. Montelukast represents the third molecule of this class which has been approved in asthma after pranlukast (1995) and zafirlukast (1996). Montelukast has been studied extensively in placebo-controlled clinical trials, in mildly or severe asthmatic patients challenged with LTD4 or exercise. A variety of acute bronchoconstricting challenges were inhibited or attenuated with all doses used. Montelukast demonstrated clinically significant improvements in the parameters of asthma control associated with an appreciable improvement in quality of life., reducing days with asthma exacerbations and allowing significant tapering of corticosteroids. Montelukast is well-tolerated and only needs to be administered once a day.

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