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ChemicalBook >> CAS DataBase List >> NEUROMEDIN U-25 (HUMAN)

NEUROMEDIN U-25 (HUMAN)

NEUROMEDIN U-25 (HUMAN) price.
  • $98 - $600
  • Product name: NEUROMEDIN U-25 (HUMAN)
  • CAS: 312306-89-1
  • MF: C141H203N41O38
  • MW: 3080.37
  • EINECS:
  • MDL Number:MFCD03457694
  • Synonyms:NEUROMEDIN U-25 (HUMAN);NMU-25 (HUMAN);GLY-ASN-HIS-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2: GNHWAVGHLM-NH2;PHE-ARG-VAL-ASP-GLU-GLU-PHE-GLN-SER-PRO-PHE-ALA-SER-GLN-SER-ARG-GLY-TYR-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2;NeuroMedin U-25 (huMan) NMU-25 (huMan);H-PHE-ARG-VAL-ASP-GLU-GLU-PHE-GLN-SER-PRO-PHE-ALA-SER-GLN-SER-ARG-GLY-TYR-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2;Neuromedin U-25 (porcine) trifluoroacetate salt;L-Aspartamide, L-phenylalanyl-L-arginyl-L-valyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-prolyl-L-phenylalanyl-L-alanyl-L-seryl-L-glutaminyl-L-seryl-L-arginylglycyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-
4 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CP3-0031-M005
  • Product descriptionNeuromedinU-25(human) ≥98%(HPLC)
  • Packaging5mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17617
  • Product descriptionNeuromedin U-25 (human)
  • Packaging500μg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17617
  • Product descriptionNeuromedin U-25 (human)
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17617
  • Product descriptionNeuromedin U-25 (human)
  • Packaging5mg
  • Price$588
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CP3-0031-M005 NeuromedinU-25(human) ≥98%(HPLC) 5mg $600 2021-12-16 Buy
Cayman Chemical 17617 Neuromedin U-25 (human) 500μg $98 2021-12-16 Buy
Cayman Chemical 17617 Neuromedin U-25 (human) 1mg $147 2021-12-16 Buy
Cayman Chemical 17617 Neuromedin U-25 (human) 5mg $588 2021-12-16 Buy

Properties

storage temp. :−20°C
form :lyophilized powder

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Neuromedin U (NMU) is a neuropeptide first demonstrated to drive smooth muscle contraction. Translated as a 174 amino acid propeptide, NMU is cleaved to different lengths in different animals. It has diverse receptor-mediated roles in vivo, as it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock. NMU-25 is the active form of NMU in humans. It binds with high affinity to receptors on human left ventricle and coronary artery (KDs = 0.26 and 0.11 nM, respectively), eliciting endothelium-independent vasoconstriction. NMU-25 also suppresses glucose-stimulated insulin secretion in human islets, and this effect is lost in NMU R165W mutants, resulting in early-onset obesity.

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