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ChemicalBook >> CAS DataBase List >> VICRIVIROC MALEATE

VICRIVIROC MALEATE

VICRIVIROC MALEATE price.
  • $86 - $13604.85
  • Product name: VICRIVIROC MALEATE
  • CAS: 599179-03-0
  • MF: C32H42F3N5O6
  • MW: 649.7009896
  • EINECS:
  • MDL Number:MFCD09833218
  • Synonyms:Vicriviroc Maleate(SCH 417690);(4,6-diMethylpyriMidin-5-yl)(4-((S)-4-((R)-2-Methoxy-1-(4-(trifluoroMethyl)phenyl)ethyl)-3-Methylpiperazin-1-yl)-4-Methylpiperidin-1-yl)Methanone fuMarate;vicriviroc Maleate salt;1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate VicrivirocMalate;Vicriviroc maleate 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate;SCH-D;VICRIVIROC MALEATE;VICRIVIROC MALEATE: SCH-D
Price11 Properties Safety Information Description
11 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • 10mg
  • 1g
  • 5G
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005096
  • Product descriptionVICRIVIROC MALEATE 95.00%
  • Packaging5G
  • Price$13604.85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3916
  • Product description(4,6-dimethylpyrimidin-5-yl)(4-(4-(2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-3-methylpiperazin-1-yl)-4-methylpiperidin-1-yl)methanone fumarate
  • Packaging5mg
  • Price$307
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28453
  • Product descriptionVicriviroc (maleate)
  • Packaging1mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28453
  • Product descriptionVicriviroc (maleate)
  • Packaging5mg
  • Price$274
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28453
  • Product descriptionVicriviroc (maleate)
  • Packaging10mg
  • Price$421
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1019
  • Product descriptionVicriviroc(maleate) 99.91%
  • Packaging5mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001343
  • Product descriptionVicrivirocmaleate 98+%
  • Packaging5mg
  • Price$179
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN12197
  • Product descriptionVicrivirocMaleate
  • Packaging5mg
  • Price$281
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7336
  • Product descriptionVicrivirocmaleate(Sch-417690) >98%
  • Packaging1g
  • Price$2800
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML2768
  • Product descriptionVicriviroc Maleate ≥98% (HPLC)
  • Packaging1MG
  • Price$94.2
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML2768
  • Product descriptionVicriviroc Maleate ≥98% (HPLC)
  • Packaging5MG
  • Price$381
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0005096 VICRIVIROC MALEATE 95.00% 5G $13604.85 2021-12-16 Buy
ApexBio Technology A3916 (4,6-dimethylpyrimidin-5-yl)(4-(4-(2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-3-methylpiperazin-1-yl)-4-methylpiperidin-1-yl)methanone fumarate 5mg $307 2021-12-16 Buy
Cayman Chemical 28453 Vicriviroc (maleate) 1mg $86 2024-03-01 Buy
Cayman Chemical 28453 Vicriviroc (maleate) 5mg $274 2024-03-01 Buy
Cayman Chemical 28453 Vicriviroc (maleate) 10mg $421 2024-03-01 Buy
ChemScene CS-1019 Vicriviroc(maleate) 99.91% 5mg $330 2021-12-16 Buy
Crysdot CD31001343 Vicrivirocmaleate 98+% 5mg $179 2021-12-16 Buy
CSNpharm CSN12197 VicrivirocMaleate 5mg $281 2021-12-16 Buy
DC Chemicals DC7336 Vicrivirocmaleate(Sch-417690) >98% 1g $2800 2021-12-16 Buy
Sigma-Aldrich SML2768 Vicriviroc Maleate ≥98% (HPLC) 1MG $94.2 2024-03-01 Buy
Sigma-Aldrich SML2768 Vicriviroc Maleate ≥98% (HPLC) 5MG $381 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO : 50 mg/mL (76.96 mM; Need ultrasonic)H2O : 25 mg/mL (38.48 mM; Need ultrasonic and warming)
form :Powder

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P314 Get medical advice/attention if you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Vicriviroc is a chemokine (C-C motif) receptor 5 (CCR5) antagonist (Ki = 2.5 nM). It selectively inhibits CCR5 over M1 and M2 muscarinic acetylcholine receptors (Kis = >10,000 nM for both) and human-ether-a-go-go (hERG) potassium channels (IC50 = 5.8 μM). Vicriviroc decreases chemotaxis induced by chemokine (C-C motif) ligand 3 (CCL3) in Ba/F3 cells expressing recombinant human CCR5 with an IC50 value of 0.91 nM. It inhibits the replication of 30 R5-tropic HIV-1 clinical isolates in peripheral blood mononuclear cells (PBMCs; EC50s = 0.04-1.4 nM) and reduces viral entry of seven drug-resistant strains of HIV-1 in U87 cells expressing CD4 and CCR5 (EC50s = 8.7-32.9 nM).

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CONIER CHEM AND PHARMA LIMITED
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Wuhan Han Sheng New Material Technology Co.，Ltd
LEAPCHEM CO., LTD.
Shanghai Acmec Biochemical Technology Co., Ltd. Chembest Research Laboratories Limited