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ChemicalBook >> CAS DataBase List >> Zafirlukast

Zafirlukast

Zafirlukast price.
  • $12 - $1593.9
  • Product name: Zafirlukast
  • CAS: 107753-78-6
  • MF: C31H33N3O6S
  • MW: 575.68
  • EINECS:
  • MDL Number:MFCD00864775
  • Synonyms:Carbamic acid, [3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-, cyclopentyl ester;Cyclopentyl 3-[2-methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl]-1-methylindole-5-carbamate;[3-[[2-Methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamic acid cyclopentyl ester;4-[5-(Cyclopentyloxycarbonylamino)-1-methyl-1H-indol-3-ylmethyl]-3-methoxy-N-(2-methylphenylsulfonyl)benzamide;IC-204219;Carbamic acid, N-[3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-, cyclopentyl ester;cyclopentyl N-{3-[(2-Methoxy-4-{[(2-Methylbenzene)sulfonyl]carbaMoyl}phenyl)Methyl]-1-Methyl-1H-indol-5-yl}carbaMate;Cyclopentyl N-[3-{[2-Methoxy-4-[(2-Methylphenyl) sulfonylcarbaMoy
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  • Activate Scientific
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
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  • Sigma-Aldrich
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Package
  • 10mg
  • 25mg
  • 50mg
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  • 1g
  • 10g
  • 5g
  • 10mM(in 1mL DMSO)
  • ManufacturerActivate Scientific
  • Product numberAS146296
  • Product descriptionZafirlukast 99%
  • Packaging250mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberG674
  • Product descriptionZafirlukast
  • Packaging50mg
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769198
  • Product descriptionCyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+%
  • Packaging10mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769198
  • Product descriptionCyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+%
  • Packaging25mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769198
  • Product descriptionCyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+%
  • Packaging50mg
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769198
  • Product descriptionCyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+%
  • Packaging100mg
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769198
  • Product descriptionCyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+%
  • Packaging250mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769198
  • Product descriptionCyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+%
  • Packaging1g
  • Price$227
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0000887
  • Product descriptionZAFIRLUKAST 95.00%
  • Packaging10MG
  • Price$121.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0000887
  • Product descriptionZAFIRLUKAST 95.00%
  • Packaging100MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0000887
  • Product descriptionZAFIRLUKAST 95.00%
  • Packaging1G
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2068
  • Product descriptionZafirlukast
  • Packaging10mM(in 1mL DMSO)
  • Price$65
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB2068
  • Product descriptionZafirlukast
  • Packaging50mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2250
  • Product descriptionZafirlukast
  • Packaging100mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2250
  • Product descriptionZafirlukast
  • Packaging250mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2250
  • Product descriptionZafirlukast
  • Packaging1g
  • Price$215
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS146296 Zafirlukast 99% 250mg $149 2021-12-16 Buy
AK Scientific G674 Zafirlukast 50mg $128 2021-12-16 Buy
Ambeed A769198 Cyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+% 10mg $12 2021-12-16 Buy
Ambeed A769198 Cyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+% 25mg $16 2021-12-16 Buy
Ambeed A769198 Cyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+% 50mg $22 2021-12-16 Buy
Ambeed A769198 Cyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+% 100mg $31 2021-12-16 Buy
Ambeed A769198 Cyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+% 250mg $69 2021-12-16 Buy
Ambeed A769198 Cyclopentyl(3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate 99+% 1g $227 2021-12-16 Buy
American Custom Chemicals Corporation API0000887 ZAFIRLUKAST 95.00% 10MG $121.8 2021-12-16 Buy
American Custom Chemicals Corporation API0000887 ZAFIRLUKAST 95.00% 100MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation API0000887 ZAFIRLUKAST 95.00% 1G $1593.9 2021-12-16 Buy
ApexBio Technology B2068 Zafirlukast 10mM(in 1mL DMSO) $65 2021-12-16 Buy
ApexBio Technology B2068 Zafirlukast 50mg $68 2021-12-16 Buy
AvaChem 2250 Zafirlukast 100mg $45 2021-12-16 Buy
AvaChem 2250 Zafirlukast 250mg $95 2021-12-16 Buy
AvaChem 2250 Zafirlukast 1g $215 2021-12-16 Buy

Properties

Melting point :139°C
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥28mg/mL
pka :4.94±0.10(Predicted)
form :solid
color :White or pink
Merck :14,10108
Stability :Stable for 2 years as supplied. Protect from exposure to moisture. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :107753-78-6(CAS DataBase Reference)
EPA Substance Registry System :Carbamic acid, N-[3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-, cyclopentyl ester (107753-78-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Zafirlukast is a potent subtype specific cysteinyl leukotriene type 1 receptor (CysLT1) antagonist; antiasthmatic. The cysteinyl-leukotrienes (CysLTs), LTC4 and LTD4, are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, augment microvascular permeability, and are vasoconstrictors of coronary arteries.

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