ailanthone
|
- $37 - $875
- Product name: ailanthone
- CAS: 981-15-7
- MF: C20H24O7
- MW: 376.4
- EINECS:
- MDL Number:MFCD01729487
- Synonyms:11β,20-Epoxy-1β,11,12α-trihydroxypicrasa-3,13(21)-diene-2,16-dione;13,21-Didehydrochaparrinone;ailanthone;Picrasa-3,13(21)-diene-2,16-dione,11,20-epoxy-1,11,12-trihydroxy-, (1b,11b,12a)-;Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1β,11β,12α)-;(1beta,11alpha,12alpha)-1,11,12-trihydroxy-11,20-epoxypicras...;2H-1,11c-(Epoxymethano)phenanthro[10,1-bc]pyran-5,10(3H,6aH);(1β,11β,12α)-11,20-Epoxy-1,11,12-trihydroxypicrasa-3,13(21)-diene-2,16-dione
22 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5MG
- 10mg
- 20mg
- 25mg
- 100mg
- ManufacturerAK Scientific
- Product numberW1315
- Product descriptionAilanthone
- Packaging25mg
- Price$638
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0004878
- Product descriptionAILANTHONE 95.00%
- Packaging5MG
- Price$500.31
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN97561
- Product descriptionAilanthone ≥98%
- Packaging10mg
- Price$418
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS015012
- Product description(1R,2R,3aS,3a1S,6aR,7aS,11S,11aS,11bR)-1,2,11-Trihydroxy-8,11a-dimethyl-3-methylene-2,3,3a,4,7,7a,11,11a-octahydro-1H-1,3a1-(epoxymethano)dibenzo[de,g]chromene-5,10(6aH,11bH)-dione
- Packaging100mg
- Price$735
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2388
- Product descriptionAilanthone
- Packaging5mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2388
- Product descriptionAilanthone
- Packaging10mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2388
- Product descriptionAilanthone
- Packaging25mg
- Price$335
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2388
- Product descriptionAilanthone
- Packaging100mg
- Price$875
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb593724
- Product descriptionAilanthone
- Packaging10mg
- Price$513.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb104670
- Product descriptionAilanthone >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb593724
- Product descriptionAilanthone
- Packaging20mg
- Price$666.4
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29194
- Product descriptionAilanthone
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29194
- Product descriptionAilanthone
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29194
- Product descriptionAilanthone
- Packaging10mg
- Price$213
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29194
- Product descriptionAilanthone
- Packaging25mg
- Price$485
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD32000027
- Product descriptionAilanthone 95+%
- Packaging5mg
- Price$200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | W1315 | Ailanthone | 25mg | $638 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0004878 | AILANTHONE 95.00% | 5MG | $500.31 | 2021-12-16 | Buy |
| Arctom | CFN97561 | Ailanthone ≥98% | 10mg | $418 | 2021-12-16 | Buy |
| Arctom | AS015012 | (1R,2R,3aS,3a1S,6aR,7aS,11S,11aS,11bR)-1,2,11-Trihydroxy-8,11a-dimethyl-3-methylene-2,3,3a,4,7,7a,11,11a-octahydro-1H-1,3a1-(epoxymethano)dibenzo[de,g]chromene-5,10(6aH,11bH)-dione | 100mg | $735 | 2021-12-16 | Buy |
| AvaChem | 2388 | Ailanthone | 5mg | $95 | 2021-12-16 | Buy |
| AvaChem | 2388 | Ailanthone | 10mg | $175 | 2021-12-16 | Buy |
| AvaChem | 2388 | Ailanthone | 25mg | $335 | 2021-12-16 | Buy |
| AvaChem | 2388 | Ailanthone | 100mg | $875 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb593724 | Ailanthone | 10mg | $513.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb104670 | Ailanthone >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb593724 | Ailanthone | 20mg | $666.4 | 2021-12-16 | Buy |
| Cayman Chemical | 29194 | Ailanthone | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 29194 | Ailanthone | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 29194 | Ailanthone | 10mg | $213 | 2024-03-01 | Buy |
| Cayman Chemical | 29194 | Ailanthone | 25mg | $485 | 2024-03-01 | Buy |
| Crysdot | CD32000027 | Ailanthone 95+% | 5mg | $200 | 2021-12-16 | Buy |
Properties
Melting point :235-237 °C
Boiling point :641.0±55.0 °C(Predicted)
Density :1.47
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO:100.0(Max Conc. mg/mL);265.67(Max Conc. mM)
form :A crystalline solid
pka :11.85±0.70(Predicted)
LogP :-0.760 (est)
Boiling point :641.0±55.0 °C(Predicted)
Density :1.47
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO:100.0(Max Conc. mg/mL);265.67(Max Conc. mM)
form :A crystalline solid
pka :11.85±0.70(Predicted)
LogP :-0.760 (est)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Ailanthone is a quassinoid that has been found in Ailanthus and has diverse biological activities. It is active against the P. falciparum strains HB-3 and Dd-2 in vitro (IC50s = 0.003 and 0.037 μg/ml, respectively). Ailanthone is phytotoxic, inhibiting radish seed germination by 88% when used at a concentration of 1 mM. It inhibits dihydrotestosterone-induced androgen receptor transcriptional activity (IC50 = 69 nM in a reporter assay), as well as the growth and colony formation of LNCaP and 22RV1 androgen receptor-expressing cells, but not androgen receptor-negative PC3 and DU145 cells, when used at a concentration of 0.1 μM. Ailanthone (2 mg/kg) reduces tumor volume in 22Rv1, LNCaP, and VCaP castration-resistant prostate cancer (CRPC) mouse xenograft models.More related product prices
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