| | 152121-47-6 Basic information More.. |
| Product Name: | SB 203580 | | Synonyms: | SB 203580 HYDROCHLORIDE;SB 2035850;4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL) 1H-IMIDAZOLE;4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL)1H-IMIDAZOLE, HCL;4-[5-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-3H-IMIDAZOL-4-YL]PYRIDINE;4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULFONYL)PHENYL]-1H-IMIDAZOL-4-YL]PYRIDINE;4-[5-(4-FLUOROPHENYL)-2-[4-(METHYLSULPHONYL)PHENYL]-1H-IMIDAZOL-4-YL]PYRIDINE HYDROCHLORIDE; 4-[5-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-4-yl]pyridine | | CAS: | 152121-47-6 | | MF: | C21H16FN3OS | | MW: | 377.43 | | EINECS: | | | Mol File: | 152121-47-6.mol |  |
Use
Water-soluble salt of SB 203580 (4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine ). Selective inhibitor of p38 mitogen-activated protein kinase (IC 50 values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38 2 respectively). Displays 100-500-fold selectivity over LCK, GSK3 and PKB . Shown to inhibit interleukin-2-induced T-cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase.
- SB 203580
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- US $3.00 / KG
- 2020-02-01
- CAS:152121-47-6
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 100KG
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152121-47-6
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