| | 2078-54-8 Basic information More.. |
| Product Name: | Propofol | | Synonyms: | 2,6-BIS(1-METHYLETHYL)PHENOL;Diprivan10;Disoprofol;PD18215;Phenol, 2,6-diisopropyl-;Phenol,2,6-bis(1-methylethyl)-;Phenol,2,6-diisopropyl-;propofol(INN) | | CAS: | 2078-54-8 | | MF: | C12H18O | | MW: | 178.27 | | EINECS: | 218-206-6 | | Mol File: | 2078-54-8.mol |  |
Use
Propofol is an injectable sedative–hypnotic used for the inductionand maintenance of anesthesia or sedation. Propofolis only slightly soluble in water with an octanol/water partitioncoefficient of 6,761:1; thus, it is formulated as an oil-inwateremulsion. The fat component of the emulsion consistsof soybean oil, glycerol, and egg lecithin. The pKa of thepropanol hydroxyl is 11 and the injectable emulsion has apH of 7 to 8.5. Formulations contain either disodium ethylenediaminetetraaceticacid (EDTA) (0.005%) or sodiummetabisulfite to retard the growth of microorganisms. EDTAis a metal chelator and patients on propofol containingEDTA for extended periods of time excrete more zinc andiron in their urine. The clinical consequence of this is notknown but the manufacturer recommends that a drug holidayor zinc supplementation be considered after 5 days of therapy.
- Propofol
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- US $1.00 / kg
- 2024-06-04
- CAS:2078-54-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10 ton
- Propofol
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- US $151.00-125.00 / kg
- 2024-06-03
- CAS:2078-54-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 8000kg
- Propofol
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- US $100.00 / kg
- 2024-04-25
- CAS:2078-54-8
- Min. Order: 1kg
- Purity: 99.9%
- Supply Ability: 20tons
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2078-54-8
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