| | 9007-12-9 Basic information More.. |
| Product Name: | Calcitonin | | Synonyms: | calcimar(salmon);calcitar;calcitrin;SALMON;CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2;CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2 SALMON;CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP-NH2;CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP-NH2 (DISULFIDE BRIDGE: 1-7) | | CAS: | 9007-12-9 | | MF: | C145H240N44O48S2 | | MW: | 3431.85 | | EINECS: | 232-693-2 | | Mol File: | 9007-12-9.mol |  |
Use
Calcitonin (thyrocalcitonin) is a 32-amino-acid polypeptidehormone secreted by parafollicular cells of the thyroidglands in response to hypocalcemia. The entire 32-residuepeptide appears to be required for activity, because smallerfragments are totally inactive. Common structural featuresof calcitonin isolated from different species are a COOHterminalprolinamide, a disulfide bond between residues 1and 7 at the NH2 terminus, and a chain length of 32 residues.Calcitonin inhibits calcium resorption from bone, causinghypocalcemia, with parallel changes in plasma phosphateconcentration. In general, calcitonin negates the osteolyticeffects of parathyroid hormone.The potential therapeutic uses of calcitonin are in thetreatment of hyperparathyroidism, osteoporosis and otherbone disorders, hypercalcemia of malignancy, and idiopathichypercalcemia.
- Calcitonin
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- US $10.00 / kg
- 2024-03-08
- CAS:9007-12-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000kg
- Calcitonin USP/EP/BP
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- US $1.10 / g
- 2021-07-29
- CAS:9007-12-9
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons min
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9007-12-9
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