| | 52-53-9 Basic information More.. |
| Product Name: | Verapamil | | Synonyms: | -2-isopropyl-;2-isopropyl-;4-dimethoxy-alpha-(1-methylethyl)-l)-;5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylv;Benzeneacetonitrile, .alpha.-3-2-(3,4-dimethoxyphenyl)ethylmethylaminopropyl-3,4-dimethoxy-.alpha.-(1-methylethyl)-;Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)- (9CI);dl-Verapamil;NSC 272306NA | | CAS: | 52-53-9 | | MF: | C27H38N2O4 | | MW: | 454.61 | | EINECS: | 200-145-1 | | Mol File: | 52-53-9.mol |  |
Use
Verapamil, 5-[. Hemodynamically, verapamil causesa change in the preload, afterload, contractility, heart rate,and coronary blood flow. The drug reduces systemic vascularresistance and mean blood pressure, with minor effectson cardiac output.Verapamil is a synthetic compound possessing slightstructural similarity to papaverine. It can be separated intoits optically active isomers, of which the levorotatory enantiomeris the most potent. It is absorbed rapidly after oraladministration. The drug is metabolized quickly and, as aresult, has low bioavailability. The liver is the main siteof first-pass metabolism, forming several products. Thepreferential metabolic step involves N-dealkylation, followedby O-demethylation, and subsequent conjugation ofthe product before elimination. The metabolites have no significantbiological activity. Verapamil has an eliminationhalf-life of approximately 5 hours.
- Verapamil USP/EP/BP
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- US $1.10 / g
- 2021-08-12
- CAS:52-53-9
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons min
- Verapamil
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- US $3.00 / KG
- 2020-01-08
- CAS:52-53-9
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 200KG
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52-53-9
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