| | 61-68-7 Basic information More.. |
| Product Name: | Mefenamic acid | | Synonyms: | in-M;Lysalgo;Mefacit;Mefenacid;Ponstan forte;ponstanforte;Ponstil;Ponstyl | | CAS: | 61-68-7 | | MF: | C15H15NO2 | | MW: | 241.29 | | EINECS: | 200-513-1 | | Mol File: | 61-68-7.mol |  |
Use
Mefenamic acid (Ponstel, Ponstan) is one of the oldestNSAIDs, introduced into the market in 1967 for mild tomoderate pain and for primary dysmenorrhea. It is rapidly absorbed with peak plasma levels occurring 2 to 4 hoursafter oral administration. It undergoes hepatic benzylic hydroxylationof its 3'methyl group regioselectively into twoinactive metabolites, 3'-hydroxymethylmefenamic acid andthe 3'carboxylate metabolite (via further oxidation of thebenzylic alcohol group). The parent drugs and these metabolitesare conjugated with glucuronic acid and excreted primarilyin the urine. Thus, although patients with knownliver deficiency may be given lower doses, it is contraindicatedin patients with preexisting renal dysfunction.Common side effects associated with its use include diarrhea,drowsiness, and headache. The possibility of blood disordershas also prompted limitation of its administration to 7days. It is not recommended for children or during pregnancy.
- Mefenamic Acid
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- US $0.00 / Kg/Bag
- 2024-05-08
- CAS:61-68-7
- Min. Order: 2Kg/Bag
- Purity: 99% up, High Density
- Supply Ability: 20 tons
- Mefenamic Acid
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- US $0.00 / kg
- 2024-04-05
- CAS:61-68-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000kg
- Mefenamic acid
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- US $45.00-35.00 / kg
- 2024-03-19
- CAS:61-68-7
- Min. Order: 1kg
- Purity: 99.8%
- Supply Ability: 200tons/year
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61-68-7
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