25812-30-0 Basic information More..
Product Name:Gemfibrozil
Synonyms:PENTANOIC ACID, 5-(2,5-DIMETHYLPHENOXY)-2,2-DIMETHYL-;5-(2,5-DIMETHYLPHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID;5-(2,5-DIMETHYL-PHENOXY)-2,2-DIMETHYL-PENTANOIC ACID;2,2-DIMETHYL-5-[2,5-DIMETHYL-PHENOXY]PENTANOIC ACID;2,2-DIMETHYL-5-(2,5-XYLYLOXY) VALERIC ACID;GEMFIBROZIL;Gemcitabine intermediates;5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic Acid, CI-719, Decrelip, Genlip, Gevilon, Lipozid, Lpur, Lopid
CAS:25812-30-0
MF:C15H22O3
MW:250.33
EINECS:247-280-2
Mol File:25812-30-0.mol
25812-30-0

Use

Gemfibrozil, 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid (Lopid), is a congener of clofibratethat was used first in the treatment of hyperlipoproteinemia inthe mid-1970s. Its mechanism of action and use are similar tothose of clofibrate. Gemfibrozil reduces plasma levels ofVLDL triglycerides and stimulates clearance of VLDL fromplasma. The drug has little effect on cholesterol plasma levelsbut does cause an increase of HDL.Gemfibrozil is absorbed quickly from the gut and excretedunchanged in the urine. The drug has a plasma half-life of1.5 hours, but reduction of plasma VLDL concentration takesbetween 2 and 5 days to become evident. The peak effect of its hypolipidemic action may take up to 4 weeks to becomemanifest.

Gemfibrozil manufacturers

  • Gemfibrozil
  • US $0.00 / kg
  • 2024-05-08
  • CAS:25812-30-0
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 20tons
  • Gemfibrozil
  • US $0.10-1.00 / kg
  • 2022-10-20
  • CAS:25812-30-0
  • Min. Order: 1kg
  • Purity: 98%min (HPLC/GC)
  • Supply Ability: 1-10000kg
  • Gemfibrozil
  • US $10.00 / Kg/Bag
  • 2021-11-16
  • CAS:25812-30-0
  • Min. Order: 1Kg/Bag
  • Purity: 99%
  • Supply Ability: 20 Tons
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