Acridine

Use

Acridine has been crystallised twice from *benzene/cyclohexane, or from aqueous EtOH, then sublimed, removing and discarding the first 25% of the sublimate. The remainder is again crystallised and sublimed, discarding the first 10-15% [Wolf & Anderson J Am Chem Soc 77 1608 1955]. Acridine can also be purified by crystallisation from n-heptane and then from ethanol/water after pre-treatment with activated charcoal, or by chromatography on alumina with pet ether in a darkened room. Alternatively, acridine can be precipitated as the hydrochloride from *benzene solution by adding HCl, after which the base is regenerated, dried at 110o/50mm, and recrystallised to constant melting point from pet ether [Cumper et al. J Chem Soc 4518 1962]. The regenerated free base may be recrystallised, chromatographed on basic alumina, then vacuum-sublimed and zone-refined. [Williams & Clarke, J Chem Soc, Faraday Trans 1 73 514 1977, Albert, The Acridines Arnold Press 1966.] It can exist in five crystalline forms and is steam volatile. It is a strong IRRITANT to skin and mucous membranes and can become a chronic irritant— handle it with CARE. [Beilstein 20/8 V 199.]

Acridine manufacturers

• Acridine
• 
• US $100.00 / kg
• 2023-01-31
• CAS:260-94-6
• Min. Order: 1kg
• Purity: 98%
• Supply Ability: 5000kg

• Acridine
• 
• US $65.00 / g
• 2021-11-02
• CAS:260-94-6
• Min. Order: 5g
• Purity: 99%
• Supply Ability: 100kg

• Acridine
• 
• US $0.00-0.00 / KG
• 2021-07-20
• CAS:260-94-6
• Min. Order: 1g
• Purity: 99%
• Supply Ability: 2000tons