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| | Ochrobirine Basic information |
| Product Name: | Ochrobirine | | Synonyms: | (5R,6'S,8'S)-6',7,8,8'-Tetrahydro-6-methylspiro[1,3-dioxolo[4,5-g]isoquinoline-5(6H),7'-[7H]indeno[4,5-d][1,3]dioxole]-6',8'-diol;d-Ochrobirine;Ochrobirine;Spiro[1,3-dioxolo[4,5-g]isoquinoline-5(6H),7'-[7H]indeno[4,5-d][1,3]dioxole]-6',8'-diol, 6',7,8,8'-tetrahydro-6-methyl-, (5R,6'S,8'S)- | | CAS: | 24181-64-4 | | MF: | C20H19NO6 | | MW: | 369.37 | | EINECS: | | | Product Categories: | | | Mol File: | 24181-64-4.mol |  |
| | Ochrobirine Chemical Properties |
| | Ochrobirine Usage And Synthesis |
| Description | A Corydalis alkaloid, this base is found in C. lutea (L.) D. C., C. ochroleuca Koch
and C. sibirica Pers. It forms colourless crystals from MeOH with I mole of
solvent, m.p. l38-9°C and has [α] 21
+ 35.9° (CHCI3). It yields a crystalline
acetate, m.p. 177°C and on treatment with Zn-amalgam is converted into an
isomeric base with m.p. 238°C. The structure of the alkaloid, deduced from
chemical and physical evidence has been confirmed by the synthesis of the
optically active form. | | References | Manske., Can. J. Res., 18B, 75 (1940)
Total synthesis:
Kametani, Hibino, Takano., Chern. Cornrnun., 925 (1971) |
| | Ochrobirine Preparation Products And Raw materials |
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