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| | 1-Boc-4-amino-4-piperidineacetic acid Basic information |
| Product Name: | 1-Boc-4-amino-4-piperidineacetic acid | | Synonyms: | 2-(4-AMINO-1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)ACETIC ACID;1-Boc-4-amino-4-piperidineacetic acid;2-(4-Amino-1-(tert-butoxycarbonyl);2-[4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid;2-(1-Boc-4-amino-4-piperidyl)acetic Acid;4-Piperidineacetic acid, 4-amino-1-[(1,1-dimethylethoxy)carbonyl]-;2-(4-Amino-1-boc-piperidin-4-yl)acetic Acid;4-Amino-1-[(1,1-dimethylethoxy)carbonyl]-4-piperidineacetic acid | | CAS: | 1159983-30-8 | | MF: | C12H22N2O4 | | MW: | 258.31 | | EINECS: | | | Product Categories: | CHIRAL CHEMICALS | | Mol File: | Mol File |  |
| | 1-Boc-4-amino-4-piperidineacetic acid Chemical Properties |
| Boiling point | 398.9±27.0 °C(Predicted) | | density | 1.158±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | pka | 4.66±0.10(Predicted) |
| | 1-Boc-4-amino-4-piperidineacetic acid Usage And Synthesis |
| Uses | 1-Boc-4-amino-4-piperidineacetic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | | Synthesis | 
A mixture of 4-oxo-piperidine- 1 -carboxylic acid tert-butyl ester (3.5 g, 17.55 mmol) (Sigma- Aldrich), malonic acid (2.0 g, 19.30 mmol) and ammonium acetate (3.1 g, 40.36 mmol) in n-BuOH was refluxed for 3 h. After cooled, white solid was collected, rinsed with EtOAc and dried in vacuo to provide the title compound 1.61 g (6.2 mmol) in 36% yield. |
| | 1-Boc-4-amino-4-piperidineacetic acid Preparation Products And Raw materials |
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