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| | DOCUSATE CALCIUM (500 MG) Basic information |
| Product Name: | DOCUSATE CALCIUM (500 MG) | | Synonyms: | DOCUSATE CALCIUM (500 MG);calcium 1,4-bis(2-ethylhexyl) bis(2-sulphosuccinate);calcium dioctyl sulfosuccinate;Bis[1,2-bis[(2-ethylhexyl)oxycarbonyl]ethanesulfonic acid] calcium salt;Bis[1-[[(2-ethylhexyl)oxy]carbonyl]-3-oxo-3-(2-ethylhexyloxy)propane-1-sulfonic acid] calcium salt;Bis[3-sulfosuccinic acid 1,4-bis(2-ethylhexyl)]calcium salt;Butanedioicacid,sulfo-,1,4-bis(2-ethylhexyl)ester,calciumsalt;docusatecalcium | | CAS: | 128-49-4 | | MF: | C20H40CaO7S | | MW: | 464.67 | | EINECS: | 204-889-8 | | Product Categories: | | | Mol File: | 128-49-4.mol |  |
| | DOCUSATE CALCIUM (500 MG) Chemical Properties |
| Boiling point | 339℃[at 101 325 Pa] | | density | 1.021[at 20℃] | | vapor pressure | 0Pa at 20℃ | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly, Heated), Methanol (Slightly) | | form | Solid | | color | White to Off-White | | Water Solubility | 6g/L at 20℃ | | Stability: | Hygroscopic | | LogP | 8.9 at 20℃ |
| | DOCUSATE CALCIUM (500 MG) Usage And Synthesis |
| Originator | Surfak,Hoechst,US,1959 | | Uses | Calcium salt of Docusate, used for the treatment of constipation, acting as a laxative or stool softener. | | Uses | Stool
softener. | | Manufacturing Process | 88 g of dioctyl sodium sulfosuccinate is first dissolved in 100 cc of isopropanol
and 25 g of calcium chloride is dissolved in 50 cc of methanol. The solutions
are then mixed and stirred for about 3 hours and then cooled with ice. The
sodium chloride which precipitates in the cool mixture is removed by filtration
and most of the alcohol is evaporated from the resulting filtrate with heat. The
liquid remaining is poured into 88 cc of water, and the resulting precipitate
washed with water until free of chloride ion. The washed calcium salt is then
dried. | | Brand name | Surfak (Hoechst-Roussel). | | Therapeutic Function | Stool softener | | Flammability and Explosibility | Non flammable |
| | DOCUSATE CALCIUM (500 MG) Preparation Products And Raw materials |
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