2-amino-N-(2,2,2-trifluoroethyl)acetamide

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CAS:359821-38-8
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CAS:359821-38-8
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CAS:359821-38-8
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2-amino-N-(2,2,2-trifluoroethyl)acetamide Basic information
Product Name:2-amino-N-(2,2,2-trifluoroethyl)acetamide
Synonyms:2-amino-N-(2,2,2-trifluoroethyl)acetamide;Acetamide, 2-?amino-?N-?(2,?2,?2-?trifluoroethyl)?-;2-trifluoroethyl)acetamide
CAS:359821-38-8
MF:C4H7F3N2O
MW:156.11
EINECS:
Product Categories:
Mol File:359821-38-8.mol
2-amino-N-(2,2,2-trifluoroethyl)acetamide Structure
2-amino-N-(2,2,2-trifluoroethyl)acetamide Chemical Properties
Boiling point 227.5±40.0 °C(Predicted)
density 1.294±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka12.87±0.46(Predicted)
form crystalline powder
color Yellow
Safety Information
HS Code 2922498590
MSDS Information
2-amino-N-(2,2,2-trifluoroethyl)acetamide Usage And Synthesis
Uses2-amino-N-(2,2,2-trifluoroethyl) acetamide, which is usually stable in the form of salt, is a key intermediate in the synthesis of fluralaner, a new broad-spectrum veterinary insecticide. 
PreparationThe method of preparing 2-amino-N-(2,2,2-trifluoroethyl) acetamide and its salt is to react the glycine protected by N-phthalyl group with trifluoroethylamine or its salt to form an amide, and remove the protective group under the action of hydrated fibril to obtain the crude product of 2- amino-N-(2,2,2-trifluoroethyl) acetamide.The crude product can be salted with acid to get a salt of 2-amino-N-(2,2, 2-trifluoroethyl) acetamide, and finally add a base to dissociate pure 2-amino-N-(2,2, 2-trifluoroethyl) ethylkuroamine.
2-amino-N-(2,2,2-trifluoroethyl)acetamide Preparation Products And Raw materials
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