ANTI-SYNTAXIN

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Company Name: Riedel-de Haen AG  
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Products Intro: Purity:IgG fraction of antiserum, lyophilized powder
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ANTI-SYNTAXIN Basic information
Product Name:ANTI-SYNTAXIN
Synonyms:ANTI RAT SYNTAXIN;ANTI-SYNTAXIN 1 RABBIT PAB;ANTI-SYNTAXIN 1, RAT;ANTI-SYNTAXIN 1, RAT (RABBIT);ANTI-SYNTAXIN;ANTI-SYNTAXIN 1;ANTI-SYNTAXIN, HUMAN;ANTI-SYNTAXIN, HUMAN (MOUSE)
CAS:
MF:
MW:0
EINECS:
Product Categories:Clone Index;HAntibodies;Alphabetical Index;Antibodies for Neurobiology;Antibodies to Neural ProteinsNeuroscience;Antibodies to Synaptic ProteinsAntibodies;Neuroscience;SM-SZ
Mol File:Mol File
ANTI-SYNTAXIN Structure
ANTI-SYNTAXIN Chemical Properties
storage temp. -20°C
form lyophilized powder
Safety Information
Hazard Codes T
Risk Statements 25-52/53
Safety Statements 45-61
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
ANTI-SYNTAXIN Usage And Synthesis
UsesMonoclonal Anti-Syntaxin antibody produced in mouse has been used in:
  • immunoblotting
  • immunohistochemistry
  • immunoprecipitation from hippocampal lysate
  • immunohistochemical analysis

General DescriptionSyntaxin is a 35kD synaptic protein capable of interacting with the synaptic vesicle protein synaptotagmin. It facilitates the docking and fusion of synaptic vesicles with the plasma membrane. Monoclonal anti-syntaxin antibody can be used to screen λ gt 11 library of rat hippocampus to isolate syntaxin cDNA clones. It can also be used in microarray and immunocytochemistry. Mouse anti-syntaxin antibody reacts specifically with membrane protein syntaxin (35 kD). The product has also shown cross reactivity for rabbit, rat and bovine but not for guinea pig.
Biochem/physiol ActionsSyntaxin 1 (STX1A) may control exocytosis in synaptic vesicles. In retina, STX1A may help in the structural formation of the inner nuclear layer (INL) and outer plexiform layer (OPL). Deletion of STX1A in mice affects the functions of hypothalamic-pituitary-adrenal axis. It may participate in spinal nociceptive plasticity promoted by peripheral nerve injury. It has been implicated in docking at synaptic vesicles of presynaptic neurotransmitter release sites.
ANTI-SYNTAXIN Preparation Products And Raw materials
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