CYCLOPIAZONIC ACID

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Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
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Products Intro: Product Name:CYCLOPIAZONIC ACID
CAS:83136-88-3
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: Shanghai Hao Zhun Biological Technology Co., Ltd.  
Tel: 15800340161
Email: info@zzsrm.com
Products Intro: Product Name:Cyclopiazonic acid
CAS:83136-88-3
Purity:100 μg/mL in dried down
Company Name: Riedel-de Haen AG  
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Products Intro: CAS:83136-88-3
Company Name: BIOMOL INTERNATIONAL, LP  
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Company Name: Alexis Corporation  
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CYCLOPIAZONIC ACID Basic information
Product Name:CYCLOPIAZONIC ACID
Synonyms:ALPHA CYCLOPIAZONIC ACID;CPA;CYCLOPIAZONIC ACID;CYCLOPIAZONIC ACID, PENICILLIUM CYCLOPIUM;PENICILLIUM CYCLOPIUM;(6AR,11AS,11BR)-REL-10-ACETYL-2,6,6A,7,11A,11B-HEXAHYDRO-7,7-DIMETHYL-9H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-9-ONE;(6AA, 10Z, 11AB, 11BA)-6A,7,11A,11B-TETRAHYDRO-10-(1-HYDROXYETHYLIDENE)-7,7- DIMETHYL-6H-PYRROLO [1',2':2,3]ISOINDOLO [4,5,6-CD]INDOLE-9,11 (2H,10H)-DIONE;6H-Pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indole-9,11(2H,7H)-dione, 6a,10,11a,11b-tetrahydro-10-(1-hydroxyethylidene)-7,7-dimethyl-, (6aR,10Z,11aS,11bR)-
CAS:83136-88-3
MF:C20H20N2O3
MW:336.38
EINECS:2005854
Product Categories:
Mol File:83136-88-3.mol
CYCLOPIAZONIC ACID Structure
CYCLOPIAZONIC ACID Chemical Properties
Melting point 245-246 °C
storage temp. −20°C
solubility DMSO: soluble
form powder
color white to off-white
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 36/37/39-45
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS UY8587000
ToxicityCyclopiazonic acid is a natural contaminant of cheese, corn, and peanuts. Due to the lack of analytical methods for quantifying cyclopiazonic acid, the amount present in the food supply and the potential health risks are uncertain. Cyclopiazonic acid distributes widely in mammalian tissues, especially skeletal muscle, and produces equally diverse cytotoxicity. This toxicant shares many pharmacological properties with antipsychotic drugs including catalepsy, hypothermia, hypokinesia, ptosis, tremor, gait disturbance, sedation without loss of righting reflex, atypical convulsion, and increased barbiturate sleeping time. The mode of action of cyclopiazonic acid involves its role as an inhibitor of Ca-ATPase.
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
CYCLOPIAZONIC ACID Usage And Synthesis
UsesCyclopiazonic Acid is an inhibitor of endoplasmic reticulum Ca2+-ATPase.
DefinitionChEBI: Alpha-cyclopiazonic acid is a member of alpha-cyclopiazonic acids. It is a conjugate acid of an alpha-cyclopiazonate. It is a tautomer of a (6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one.
CYCLOPIAZONIC ACID Preparation Products And Raw materials
Tag:CYCLOPIAZONIC ACID(83136-88-3) Related Product Information
cyclopiazonic acid imine CYCLOPIAZONIC ACID-BSA CONJUGATE CYCLOPIAZONIC ACID