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(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide

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(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: CAS:432531-71-0
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: Finetech Industry Limited
Tel: +86-27-87465837 +8618971612321
Email: info@finetechnology-ind.com
Products Intro: Product Name:Necrosulfonamide
CAS:432531-71-0
Purity:98% Package:1g,10g,25g,500g,1kg
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:Necrosulfonamide HCl
CAS:432531-71-0
Purity:98% Package:5mg Remarks:V34662
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:Necrosulfonamide
CAS:432531-71-0
Package:10 mg；100 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:Necrosulfonamide
CAS:432531-71-0
Purity:>=98% Package:$156.9/1mg;$327.9/10mg;Bulk package Remarks:98%
(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide Basic information
Product Name:(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide
Synonyms:(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide;Necrosulfonami;N-[4-[[(3-Methoxypyrazinyl)aMino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenaMide;(E)-N-[4-[(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophen-2-yl)prop-2-enamide;MLKL Inhibitor, Necrosulfonamide - CAS 432531-71-0 - Calbiochem;Necrosulfonamide(b);2-Propenamide, N-[4-[[(3-methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-;(E/Z)-Necrosulfonamide
CAS:432531-71-0
MF:C18H15N5O6S2
MW:461.47
EINECS:
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Mol File:432531-71-0.mol
(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide Structure
(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide Chemical Properties
storage temp. +2C to +8C
solubility DMSO:100.0(Max Conc. mg/mL);216.7(Max Conc. mM)
form Dark yellow solid
Safety Information
MSDS Information
(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide Usage And Synthesis
Chemical PropertiesYellow Solid
UsesNecrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.
DefinitionChEBI: Necrosulfonamide is a sulfonamide that is a 3-methoxypyrazin-2-yl derivative of (E)-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide. Necrosulfonamide specifically blocks necrosis downstream of the activation of RIP3 (the receptor-interacting serine-threonine kinase 3), a key signalling molecule in the programmed necrosis (necroptosis) pathway. It is a sulfonamide, a member of pyrazines and a member of thiophenes.
(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide Preparation Products And Raw materials
Tag:(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide(432531-71-0) Related Product Information
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