| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:GW 766994
CAS:408303-43-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | GW 766994 Basic information |
| Product Name: | GW 766994 | | Synonyms: | GW 766994;GW 994;Benzamide, 4-[[[[[[(2S)-4-[(3,4-dichlorophenyl)methyl]-2-morpholinyl]methyl]amino]carbonyl]amino]methyl]- | | CAS: | 408303-43-5 | | MF: | C21H24Cl2N4O3 | | MW: | 451.35 | | EINECS: | | | Product Categories: | | | Mol File: | 408303-43-5.mol |  |
| | GW 766994 Chemical Properties |
| Boiling point | 685.8±55.0 °C(Predicted) | | density | 1.331±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:56.0(Max Conc. mg/mL);124.07(Max Conc. mM) | | form | A solid | | pka | 13.40±0.46(Predicted) |
| | GW 766994 Usage And Synthesis |
| Description | GW 766994 is an antagonist of chemokine (C-C motif) receptor 3 (CCR3) with a Ki value of 13.8 nM in an assay of eosinophil chemotaxis induced by chemokine (C-C motif) ligand 11 (CCL11). It decreases CCL11-induced cyclin-dependent kinase 5 (Cdk5) and tau phosphorylation and production of amyloid β (1-42) (Aβ42) in isolated mouse hippocampal neurons when used at a concentration of 10 μM. |
| | GW 766994 Preparation Products And Raw materials |
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