| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Tau-441 human
Purity:recombinant, lyophilized powder, expressed in HEK 293 cells Package:50UG Remarks:SAE0076-50UG
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Remarks:recombinant, expressed in E. coli, ≥90% (SDS-PAGE), lyophilized powder
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | TAU-441 HUMAN Basic information |
| | TAU-441 HUMAN Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder |
| | TAU-441 HUMAN Usage And Synthesis |
| Uses | Tau-441 human has been used to study its effects on mitochondrial transport velocities found in glial cells. | | General Description | Tau-441 human, recombinant, is an isoform of Tau, variant 2N4R, having 4 microtubule binding repeats (R) and 2 amino terminal inserts (N). Tau is a family of neuronal microtubule-associated proteins. Tau, a phosphoprotein is considered as an important microtubule associated protein (MAP) of a mature neuron. The 2N4R tau consists of 441 amino acids (tau441) and is considered as the largest size human brain tau. In human brain, tau is present in six molecular isoforms. | | Biochem/physiol Actions | Microtubule associated protein tau (MAPT) plays an important role in the assembly and maintenance of the microtubule structure. Loss of expression of MAPT results in developmental delay and learning disability. The protein has been associated with pathology of Alzheimer′s disease (AD). |
| | TAU-441 HUMAN Preparation Products And Raw materials |
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