Company Name: |
Amatek Scientific Co. Ltd.
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0512-56316828 4008675858 |
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sales@amateksci.com |
Products Intro: |
Product Name:2-AMino-3'-hydroxy-acetophenone HCl CAS:14665-75-9 Purity:97% HPLC Package:1g;5g;25g;100g
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| 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Basic information |
Product Name: | 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE | Synonyms: | 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE;2-AMino-3'-hydroxy-acetophenone HCl;2-Amino-1-(3-hydroxyphenyl)ethanone Hydrochloride;2-amino-1-(3-hydroxy-phenyl)-ethanone;Phenylephrine Impurity 26 | CAS: | 14665-75-9 | MF: | C8H9NO2.ClH | MW: | 187.625 | EINECS: | | Product Categories: | | Mol File: | 14665-75-9.mol | |
| 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Chemical Properties |
Melting point | 221–222°C | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | form | Solid | color | Pale Beige to Brown |
| 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Usage And Synthesis |
Uses | 2-Amino-3’-hydroxy-acetophenone Hydrochloride is a reactant in the synthesis of TRPM8 modulators. | Preparation | Preparation by hydrolysis of m-(benzoyloxy)- a-amino-acetophenone hydrochloride (SM) (m.p. 202–205°) with refluxing 10% hydrochloric acid (quantitative yield), for 2 h (80%); ? with 37% hydrochloric acid in chlorobenzene at 90° for 3 h (90%). SM was obtained by reaction of hexamethylenetetramine with m-(benzoyloxy)- a-bromoacetophenone (m.p. 162°) in ethanol in the presence of 37% hydrochloric acid for 6 h at r.t. (75%). |
| 2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Preparation Products And Raw materials |
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