| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:AMT hydrochloride;2-AMino-5,6-dihydro-6-Methyl-4H-1,3-thiazinehydrochloride
CAS:21463-31-0
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| | AMT HYDROCHLORIDE Basic information |
| Product Name: | AMT HYDROCHLORIDE | | Synonyms: | 5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZIN-2-AMINE, HYDROCHLORIDE;AMT HYDROCHLORIDE;AMT HCL;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HYDROCHLORIDE;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HCL;4H-1 | | CAS: | 21463-31-0 | | MF: | C5H11ClN2S | | MW: | 166.67 | | EINECS: | | | Product Categories: | | | Mol File: | 21463-31-0.mol |  |
| | AMT HYDROCHLORIDE Chemical Properties |
| Melting point | 146-150°C | | storage temp. | 0-6°C | | solubility | DMF: >8 mg/ml; DMSO: >16 mg/ml; Ethanol: >25 mg/ml; Water: >25 mg/ml | | form | A crystalline solid | | Water Solubility | Soluble to 10 mM in water |
| Provider | Language |
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ACROS
| English |
| | AMT HYDROCHLORIDE Usage And Synthesis |
| Description | AMT is a potent, relatively selective inhibitor of iNOS with a Ki of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations; the IC50 values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively. | | Chemical Properties | white to off-white powder | | Uses | AMT Hydrochloride is a potent and selective inhibitors of inducible nitric oxide synthase, which may lead to therapeutic applications in the treatment of inflammatory and autoimmune diseases. | | Biological Activity | Potent, selective and reversible inhibitor of iNOS (IC 50 = 3.6 nM; approximately 30 and 40 times selective over nNOS and eNOS respectively). | | storage | Desiccate at +4°C |
| | AMT HYDROCHLORIDE Preparation Products And Raw materials |
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