- Thiol-PEG2-t-butyl ester
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- $0.00 / 500mg
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2024-03-27
- CAS:1398044-50-2
- Min. Order: 500mg
- Purity: >98.00%
- Supply Ability: 500mg
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| | Thio-PEG2-t-butyl ester Basic information |
| Product Name: | Thio-PEG2-t-butyl ester | | Synonyms: | Thio-PEG2-t-butyl ester;Thiol-PEG2-t-butyl ester;Thiol-PEG2-t-butly ester;SH-PEG2-CH2CH2COOtBu;HS-PEG2-COOtBu;HS-PEG2-CH2CH2COOtBu;Thiol-PEG3-t-butly ester;Propanoic acid, 3-[2-(2-mercaptoethoxy)ethoxy]-, 1,1-dimethylethyl ester | | CAS: | 1398044-50-2 | | MF: | C11H22O4S | | MW: | 250.35 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1398044-50-2.mol |  |
| | Thio-PEG2-t-butyl ester Chemical Properties |
| Boiling point | 330.6±27.0 °C(Predicted) | | density | 1.041±0.06 g/cm3(Predicted) | | pka | 9?+-.0.10(Predicted) |
| | Thio-PEG2-t-butyl ester Usage And Synthesis |
| Biological Activity | Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Thio-PEG2-t-butyl ester Preparation Products And Raw materials |
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