雷扎芬净
| 中文名称 | 雷扎芬净 |
|---|---|
| 中文同义词 | 雷扎芬净;棘白菌素;瑞扎芬净;醋酸雷扎芬净 |
| 英文名称 | Rezafungin |
| 英文同义词 | SP-3025;Rezafungin;long-lasting,infection,SP3025,CD 101,antifungal,Fungal,inhibit,echinocandin,CD-101,Inhibitor,Rezafungin,SP 3025;Bexagliflozin Impurity 38 |
| CAS号 | 1396640-59-7 |
| 分子式 | C63H85N8O17 |
| 分子量 | 1226.41 |
| EINECS号 | |
| 相关类别 | 医药原料;贝尔卡主打;武汉贝尔卡主打 |
| Mol文件 | 1396640-59-7.mol |
| 结构式 |  |
雷扎芬净 性质
| InChIKey | LNFCWEXGZIEGJW-WIQSWMFQNA-O |
|---|
Rezafungin (Biafungin) 是下一代，广谱且持久的棘皮菌素。Rezafungin 显示对念珠菌，曲霉和肺孢子菌具有有效的抗真菌活性。
Rezafungin (Biafungin) shows potent in vivo efficacy as prophylaxis against Pneumocystis in an in vivo mouse infection model.
| Animal Model: | C3H/HeN mice |
| Dosage: | 1 mg/kg |
| Administration: | Intraperitoneal injection; once daily for 6 days |
| Result: | Significantly reduced nuclei and asci burdens. |