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| Methyl indole-4-carboxylate Basic information |
| Methyl indole-4-carboxylate Chemical Properties |
Melting point | 68-71 °C(lit.) | Boiling point | 306.47°C (rough estimate) | density | 1.1999 (rough estimate) | refractive index | 1.5060 (estimate) | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | solubility | soluble in Methanol | pka | 15.80±0.30(Predicted) | form | Crystalline Powder | color | Off-white to green | BRN | 141826 | InChIKey | WEAXQUBYRSEBJD-UHFFFAOYSA-N | CAS DataBase Reference | 39830-66-5(CAS DataBase Reference) |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 26-36 | WGK Germany | 3 | HazardClass | IRRITANT | HS Code | 29339900 |
| Methyl indole-4-carboxylate Usage And Synthesis |
Chemical Properties | off-white to green crystalline powder | Uses | • ;Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators1• ;Reactant for preparation of cytotoxic agents against multidrug-resistant cancer cells2• ;Reactant for preparation of inhibitor for β-tryptase3• ;Reactant for preparation of histamine H3 antagonists4• ;Reactant for preparation of JNK3 MAP kinase inhibitors5• ;Reactant for preparation of nucleosides6 | Uses | - Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Reactant for preparation of cytotoxic agents against multidrug-resistant cancer cells
- Reactant for preparation of inhibitor for β-tryptase
- Reactant for preparation of histamine H3 antagonists
- Reactant for preparation of JNK3 MAP kinase inhibitors
- Reactant for preparation of nucleosides
| Synthesis Reference(s) | Journal of Heterocyclic Chemistry, 26, p. 1405, 1989 DOI: 10.1002/jhet.5570260533 Chemical and Pharmaceutical Bulletin, 29, p. 249, 1981 DOI: 10.1248/cpb.29.249 | General Description | The IR and UV spectra of methyl indole-4-carboxylate was studied. |
| Methyl indole-4-carboxylate Preparation Products And Raw materials |
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