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1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)methyl]-

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1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)methyl]- Basic information
Product Name:1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)methyl]-
Synonyms:2-Amino-1-(4-methylbenzyl)benzimidazole;1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)methyl]-
CAS:37743-74-1
MF:C15H15N3
MW:237.3
EINECS:
Product Categories:
Mol File:37743-74-1.mol
1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)methyl]- Structure
1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)methyl]- Chemical Properties
Boiling point 462.0±48.0 °C(Predicted)
density 1.18±0.1 g/cm3(Predicted)
storage temp. Room Temperature
solubility CHCl3, DCM, MeOH, Acetone, Acetonitrile
pka6.66±0.10(Predicted)
Safety Information
MSDS Information
1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)methyl]- Usage And Synthesis
Uses2-Amino-1-(4-methylbenzyl)benzimidazole is an intermediate in the synthesis of Yan 7874 (Y100510) which is a potential drug in the treatment of narcolepsy, insomnia and maybe other sleep and vigilance disorders. Yan 7874 is a orexin 2 receptor agonist, yet the efficacy of Yan 7874 also appears weak, and should also be clearly improved to make it useful as a drug or research tool.
1H-Benzimidazol-2-amine, 1-[(4-methylphenyl)methyl]- Preparation Products And Raw materials
Raw materials2-Aminobenzimidazole-->4-Methylbenzyl chloride
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