| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:PipaMperone Dihydrochloride
CAS:2448-68-2
Package:100Mg,10Mg
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| | PipaMperone Dihydrochloride Basic information |
| | PipaMperone Dihydrochloride Chemical Properties |
| Melting point | 203-218°C | | storage temp. | Hygroscopic, Refrigerator, Under Inert Atmosphere | | solubility | H2O: ~50mg/mL | | form | powder | | color | white | | Stability: | Hygroscopic |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 1 | | RTECS | DW1060000 | | Toxicity | mouse,LD50,intravenous,71mg/kg (71mg/kg),Drugs in Japan Vol. 6, Pg. 631, 1982. |
| | PipaMperone Dihydrochloride Usage And Synthesis |
| Chemical Properties | Off-White to Pale Yellow Solid | | Uses | Pipamperone dihydrochloride may be used:
- as an internal standard in liquid chromatography with coulometric detection
- as an antipsychotic drugs to test its interaction with human ether-a-go-go-related gene (hERG) channel
- as an internal standard to spike human colostrum samples for reversed phase liquid chromatography- ultraviolet (LC-UV) analysis
| | Uses | Antipsychotic. | | Definition | ChEBI: A hydrochloride resulting from the reaction of pipamperone with 2 mol eq. of hydrogen chloride. It is used as an antipsychotic. | | Biochem/physiol Actions | Pipamperone, a butyrophenone derivative is a pharmacological chaperone and is a membrane-permeable dopamine receptor D4 (DRD4) antagonist. The affinity of pipamperone is higher for DRD4 and 5-hydroxytryptamine 2A receptor (5-HT2A) in comparison with DRD2. It may be useful therapeutic in treating behavioral disorders and psychomotor agitation symptoms. |
| | PipaMperone Dihydrochloride Preparation Products And Raw materials |
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