Log in | Join Free | china | japan | germany

Z-FL-COCHO

Request For Quotation
Z-FL-COCHO Suppliers list
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:Cathepsin S inhibitor
CAS:1373215-15-6
Purity:>98% Package:10mg Remarks:BOC Sciences also provides custom synthesis services for Cathepsin S inhibitor.
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:LY-3000328
CAS:1373215-15-6
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: Baoji Guokang Bio-Technology Co., Ltd.
Tel: 0917-3909592 13892490616
Email: gksales1@gk-bio.com
Products Intro: Product Name:Cathepsin S inhibitor
CAS:1373215-15-6
Purity:0.99 Package:5KG;1KG
Company Name: LEAP CHEM CO., LTD.
Tel: +86-852-30606658
Email: market18@leapchem.com
Products Intro: Product Name:Cathepsin S inhibitor
CAS:1373215-15-6
Package:1g; 5g; 25g; 1kg; 5kg; 25kg
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:Cathepsin S inhibitor
CAS:1373215-15-6
Purity:98%+ Package:10mg,500mg,1g,5g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing

Z-FL-COCHO manufacturers

  • Cathepsin S inhibitor
  • Cathepsin S inhibitor pictures
  • $15.00 / 1KG
  • 2021-07-13
  • CAS:1373215-15-6
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • Cathepsin S inhibitor
  • Cathepsin S inhibitor pictures
  • $15.00 / 1KG
  • 2021-07-10
  • CAS:1373215-15-6
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
Z-FL-COCHO Basic information
Product Name:Z-FL-COCHO
Synonyms:Z-FL-COCHO;((3R,4S)-4-((4-FLUOROBENZOYL)AMINO)-6-(4-(OXETAN-3-YL)PIPERAZIN-1-YL)CHROMAN-3-YL)N-METHYLCARBAMATE;CATHEPSIN S INHIBITOR;N-[(3R,4S)-3,4-Dihydro-3-[[(methylamino)carbonyl]oxy]-6-[4-(3-oxetanyl)-1-piperazinyl]-2H-1-benzopyran-4-yl]-4-fluorobenzamide;LY 3000328;Benzamide, N-[(3R,4S)-3,4-dihydro-3-[[(methylamino)carbonyl]oxy]-6-[4-(3-oxetanyl)-1-piperazinyl]-2H-1-benzopyran-4-yl]-4-fluoro-;(3R,4S)-4-(4-fluorobenzamido)-6-(4-(oxetan-3-yl)piperazin-1-yl)chroman-3-yl methylcarbamate;CATHEPSIN S INHIBITOR ;LY-3000328;LY3000328
CAS:1373215-15-6
MF:C25H29FN4O5
MW:484.52
EINECS:
Product Categories:
Mol File:Mol File
Z-FL-COCHO Structure
Z-FL-COCHO Chemical Properties
Boiling point 701.6±60.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≥24.25 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form Powder
pka12.50±0.46(Predicted)
Safety Information
HS Code 2934999090
MSDS Information
Z-FL-COCHO Usage And Synthesis
DescriptionLY3000328 is a potent cathepsin S inhibitor (IC50 = 7.7 nM for the human enzyme). It is selective for cathepsin S over cathepsin L, K, B, and V (IC50s = >10,000, >10,000, 4,390, and 21,500 nM, respectively). LY3000328 (1-30 mg/kg) reduces aortic diameter in a mouse model of calcium chloride-induced abdominal aortic aneurysm.
UsesLY 3000328 is a cathepsin S inhibitor for treatment of abdominal aortic aneurysm. Further provides methods for treating plaque instability, atherosclerosis, or autoimmune disorders such as rheumatoid arthritis, psoriasis, and lupus comprising administering a therapeutically effective amount of a disclosed compound.
targetcathepsin S
references[1] wiener jj, sun s, thurmond rl. recent advances in the design of cathepsin s inhibitors. curr top med chem. 2010;10(7):717-32.
[2] lee-dutra a, wiener dk, sun s. cathepsin s inhibitors: 2004-2010. expert opin ther pat. 2011;21(3):311-37.
Z-FL-COCHO Preparation Products And Raw materials
Tag:Z-FL-COCHO(1373215-15-6) Related Product Information