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| | (5S,16S,19E)-3,17-Dihydroxy-5,16-cyclo-19,20-didehydrocorynan-16-carboxylic acid methyl ester Basic information |
| Product Name: | (5S,16S,19E)-3,17-Dihydroxy-5,16-cyclo-19,20-didehydrocorynan-16-carboxylic acid methyl ester | | Synonyms: | Voacarpine;3,17-Dihydroxysarpagane-16-carboxylic acid methyl ester;(5S,16S,19E)-3,17-Dihydroxy-5,16-cyclo-19,20-didehydrocorynan-16-carboxylic acid methyl ester;Sarpagan-16-carboxylic acid, 3,17-dihydroxy-, methyl ester | | CAS: | 3650-53-1 | | MF: | C21H24N2O4 | | MW: | 368.43 | | EINECS: | | | Product Categories: | | | Mol File: | 3650-53-1.mol |  |
| | (5S,16S,19E)-3,17-Dihydroxy-5,16-cyclo-19,20-didehydrocorynan-16-carboxylic acid methyl ester Chemical Properties |
| Melting point | 227-8°C | | Boiling point | 548.9±50.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | pka | 13.06±0.40(Predicted) |
| | (5S,16S,19E)-3,17-Dihydroxy-5,16-cyclo-19,20-didehydrocorynan-16-carboxylic acid methyl ester Usage And Synthesis |
| Description | An alkaloid isolated from Voacanga chalotiana, this base has [α]20D + 43.5° ± 4° (MeOH). It forms a methiodide, m.p. 215-6°C; [α]20D - 12° ± 4° (MeOH); the
O,N-diacetyl derivative, m.p. 212-3°C and the O,N-ditosyl compound, m.p.
193-4°C. When heated with mineral acids, the alkaloid gives isovoacarpine, m.p.
227.5-228.5°C, giving an N-acetyl derivative, m.p. 256-7°C. | | References | Denayer-Tournay et al., Bull. Soc. Chim. Belg., 74, 170 (1965) |
| | (5S,16S,19E)-3,17-Dihydroxy-5,16-cyclo-19,20-didehydrocorynan-16-carboxylic acid methyl ester Preparation Products And Raw materials |
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