| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Methyl-3,4-dephostatin
Purity:>98% (HPLC), powder Package:1MG Remarks:M9440-1MG
|
| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Product Name:Methyl-3,4-dephostatin
Purity:>98% (HPLC), powder
|
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Email: |
|
| Products Intro: |
|
| Company Name: |
VWR International
|
| Tel: |
800 932 5000 |
| Email: |
solutions@vwr.com |
| Products Intro: |
|
|
| | 3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE Basic information |
| | 3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: 18 mg/mL, soluble | | form | powder | | color | red-brown |
| | 3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE Usage And Synthesis |
| Uses | Methyl-3,4-dephostatin has been used as:
- an inhibitor for methyltransferases
- a kinase-related inhibitor for human transglutaminase
- a cysteine binding compound for screening its effect on C-terminal domain (CTD) of human immunodeficiency virus (HIV-1) capsid protein
| | Biochem/physiol Actions | Methyl-3,4-dephostatin is a tyrphostin-related compound isolated from Streptomyces MJ742-NF5 strain. It favors nerve growth factor-based neurite formation in pheochromocytoma PC12 cells. Being a stable analog of the nitrosoaniline dephostatin, it can mimic phosphotyrosine substrate for Tyrosyl-DNA phosphodiesterase I (TdpI). |
| | 3,4-DIHYDROXY-N-METHYL-N-NITROSOANILINE Preparation Products And Raw materials |
|