Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate

Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Suppliers list
Company Name: NewCan Biotech Limited  
Tel: +86-0571-86912261 +86-15658003402
Email: sales@newcanbio.com
Products Intro: Product Name:3',5'-DI-O-Acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine
CAS:85267-60-3
Purity:98% Package:mgs,gs,kgs
Company Name: Zhengzhou Chemprize Biotech Co., Ltd.  
Tel: 15981919713
Email: sales@chemprize.com
Products Intro: Product Name:3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine
CAS:85267-60-3
Purity:95% Package:1g;5g;10g;100g
Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Basic information
Product Name:Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate
Synonyms:Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate;3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine
CAS:85267-60-3
MF:C18H24N2O7Si
MW:408.48
EINECS:
Product Categories:
Mol File:85267-60-3.mol
Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Structure
Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Chemical Properties
density 1.27±0.1 g/cm3(Predicted)
pka8.83±0.10(Predicted)
Safety Information
MSDS Information
Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Usage And Synthesis
Uses3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine can be used as organic intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis1.jpg
1.Add DMAP (0.16 mmol, 20 mg) to a stirred suspension of 2'-deoxyuridine (1 mmol, 228 mg) in acetic anhydride (7.5 mL).2.Observe the reaction mixture become homogenous for 6 hours.3.Remove the volatiles in vacuum.4.Purify the residue by flash chromatography on silica gel eluted with EA/cyclohexane (4:1 → 19:1, v/v) to obtain 3',5'-di-O-acetyl-2'-deoxyuridine.
Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate Preparation Products And Raw materials
Raw materials3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE-->Trimethylsilylacetylene
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