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| | (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Basic information |
| Product Name: | (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate | | Synonyms: | (S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE;(S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE;(S)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE;(S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENSULFONATE;(S)-(+)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE;(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL-4-METHYLBENZENESULFONATE;2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE;2,2-DIMETHYL-4(S)-4-(P-TOLYLSULFONYL)METHYL-1,3-DIOXALANE | | CAS: | 23735-43-5 | | MF: | C13H18O5S | | MW: | 286.34 | | EINECS: | | | Product Categories: | chiral;Chiral Building Blocks;Dioxanes & Dioxolanes;Dioxolanes;Glycidyl Compounds, etc. (Chiral);Synthetic Organic Chemistry | | Mol File: | 23735-43-5.mol |  |
| | (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Chemical Properties |
| Melting point | 29-31 °C | | alpha | 4.2 º (c=10, abs.alcohol) | | Boiling point | 398.71°C (rough estimate) | | density | 1.208 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.506(lit.) | | Fp | >230 °F | | storage temp. | Inert atmosphere,2-8°C | | form | powder to lump to clear liquid | | color | White or Colorless to Light yellow | | optical activity | [α]26/D +7.5°, c = 2% in DMF | | BRN | 89799 | | CAS DataBase Reference | 23735-43-5(CAS DataBase Reference) |
| | (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors. |
| | (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Preparation Products And Raw materials |
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