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| | 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride Basic information |
| Product Name: | 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride | | Synonyms: | 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride;1-(1,4-Benzodioxan-2-ylmethyl)piperidine hydrochloride;1,4-Benzodioxan, 2-(1-piperidylmethyl)-, hydrochloride;2-(1-Piperidylmethyl)-1,4-benzodioxan hydrochloride;2-Piperidinomethyl-1,4-benzodioxan hydrochloride;933F;933F Hydrochloride;Benodaine hydrochloride | | CAS: | 135-87-5 | | MF: | C14H20ClNO2 | | MW: | 269.7671 | | EINECS: | 205-222-3 | | Product Categories: | | | Mol File: | 135-87-5.mol | ![1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride Structure](CAS/GIF/135-87-5.gif) |
| | 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride Chemical Properties |
| Melting point | 229-231 °C | | storage temp. | Store at -20°C | | solubility | Chloroform: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | | form | Solid |
| Toxicity | LD50 oral in mouse: 502mg/kg |
| | 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride Usage And Synthesis |
| Description | Piperoxan is an α2-adrenergic receptor (α2-AR) antagonist (Kis = 5.4, 2, and 1.3 nM for α2A-, α2B-, and α2C-ARs, respectively) and a first generation histamine receptor antagonist. It reverses decreases in systolic blood pressure induced by clonidine in spontaneously hypertensive rats when administered at a dose of 10 mg/kg. | | Safety Profile | Poison by
intraperitoneal and intravenous routes.
Moderately toxic by ingestion and
subcutaneous routes. Experimental
reproductive effects. When heated to
decomposition it emits very toxic fumes of
NO, and HCl. |
| | 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperidinium chloride Preparation Products And Raw materials |
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